Novel SNPs in IGF1, GHR and IGFBP-3 genes reveal significant association with growth traits in Indian goat breeds

被引：18

作者：

Sharma, Anurodh ^{[1
]}

Dutt, Gautam ^{[2
]}

Sivalingam, Jayakumar ^{[1
]}

Singh, M. K. ^{[3
]}

Pathodiya, O. P. ^{[4
]}

Khadda, B. S. ^{[5
]}

Dixit, S. P. ^{[1
]}

机构：

[1] NBAGR, Karnal, Haryana, India

[2] Dr BR Ambedkar Univ, Agra, Uttar Pradesh, India

[3] Cent Inst Res Goats, Mathura, India

[4] Maharana Pratap Univ Agr & Technol, Udaipur, Rajasthan, India

[5] Cent Hort Expt Stn, Godhara, Gujarat, India

来源：

SMALL RUMINANT RESEARCH | 2013年 / 115卷 / 1-3期

关键词：

IGF-1; GHR and IGFBP-3; SNP; Jamunapari; Sirohi; Goat; SINGLE NUCLEOTIDE POLYMORPHISMS; HORMONE RECEPTOR GENES; I GENE; INSULIN; INSULIN-LIKE-GROWTH-FACTOR-1; CATTLE; SIZE; BONE;

D O I：

10.1016/j.smallrumres.2013.08.001

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The present study was conducted to investigate the effect of genetic polymorphisms in IGF1, GHR and IGFBP-3 genes on body weight of Sirohi and Jamunapari breeds of India. A panel of 80 samples belonging to nine Indian goat breeds was used for SNP identification and a total of 18 SNPs in IGF1, 5 SNPs in GHR and 8 SNPS in IGFBP-3 genes were identified. All the SNPs identified in nine breeds were genotyped in 309 goats. Statistical analysis revealed that two SNPs of IGF-1, one SNP of GHR and one SNP of IGFBP-3 genes have significant association with body weight in Sirohi breed of goat at different ages and only 1 SNP of GHR gene was found to be associated with body weight at birth in Jamunapari breed of goat. The findings of the present study can be used for selection of animals with superior growth performance. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：7 / 14

页数：8

共 14 条

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Sharma, Anurodh
Dutt, Gautam
Jayakumar, S.
Saroha, Vinita
Dixit, S. P.
JOURNAL OF APPLIED ANIMAL RESEARCH, 2014, 42 (03) : 361 - 365
[2] Genetic variability of bovine GHR, IGF-1 and IGFBP-3 genes in Indian cattle and buffalo
Ramesha, K. P.
Rao, Akhila
Basavaraju, M.
Geetha, G. R.
Kataktalware, M. A.
Jeyakumar, S.
SOUTH AFRICAN JOURNAL OF ANIMAL SCIENCE, 2015, 45 (05) : 485 - 493
[3] Associations Between IGF1, IGFBP2 and TGFβ3 Genes Polymorphisms and Growth Performance of Broiler Chicken Lines
Hosnedlova, Bozena
Vernerova, Katerina
Kizek, Rene
Bozzi, Riccardo
Kadlec, Jaromir
Curn, Vladislav
Kouba, Frantisek
Fernandez, Carlos
Machander, Vlastislav
Horna, Hana
ANIMALS, 2020, 10 (05):
[4] Association analysis for SNPs of MSTN and IGFBP-3 genes with body size and other production traits in Liaoning Cashmere Goats
Sun, Yinggang
Cai, Weidong
Zhang, Xinjiang
Hui, Taiyu
Xu, Yanan
Han, Di
Dou, Xingtang
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Wang, Jiaming
Lin, Guangyu
Wang, Lingling
Hao, Jianjun
Fu, Shuqing
Wu, Yanzhi
Chen, Rui
Qin, Yuting
Zhang, Yu
Gu, Ming
Bai, Zhixian
Wang, Zeying
ANIMAL BIOTECHNOLOGY, 2023, 34 (05) : 1796 - 1806
[5] Novel SNPs in the caprine stearoyl-CoA desaturase (SCD) and decorin (DCN) genes that are associated with growth traits in Chinese goat breeds
Zhongqi Chen
Jiajie Sun
Zhuanjian Li
Xianyong Lan
Chunlei Zhang
Yujiao Qu
Yanli Liu
Xingtang Fang
Chuzhao Lei
Hong Chen
Molecular Biology Reports, 2011, 38 : 3121 - 3127
[6] Novel SNPs in the caprine stearoyl-CoA desaturase (SCD) and decorin (DCN) genes that are associated with growth traits in Chinese goat breeds
Chen, Zhongqi
Sun, Jiajie
Li, Zhuanjian
Lan, Xianyong
Zhang, Chunlei
Qu, Yujiao
Liu, Yanli
Fang, Xingtang
Lei, Chuzhao
Chen, Hong
MOLECULAR BIOLOGY REPORTS, 2011, 38 (05) : 3121 - 3127
[7] EVALUATION OF POLYMORPHISM IN IGF-I AND IGFBP-3 GENES AND THEIR RELATIONSHIP WITH TWINNING RATE AND GROWTH TRAITS IN MARKHOZ GOATS
Rasouli, Sahar
Abdolmohammadi, Alireza
Zebarjadi, Alireza
Mostafaei, Ali
ANNALS OF ANIMAL SCIENCE, 2017, 17 (01): : 89 - 103
[8] Identification of SNPs in the second intron of IGF2BP1 and their Association with growth traits in Nanjiang Yellow goat
Chen, Shuheng
Xu, Liang
Leng, Junchen
Chen, Zitong
Chen, Yu.
Li, Li.
Zhang, Hongping
Li, Mingzhou
Cao, Jiaxue
ANIMAL BIOTECHNOLOGY, 2025, 36 (01)
[9] Polymorphism in genes of growth hormone receptor (GHR) and insulin-like growth factor-1 (IGF1) and its association with both the IGF1 expression in liver and its level in blood in Polish Holstein-Friesian cattle
Maj, Andrzej
Snochowsk, Marek
Siadkowska, Eulalia
Rowinska, Barbara
Lisowski, Pawel
Robakowska-Hyzorek, Dagmara
Oprzadek, Jolanta
Grochowska, Renata
Kochman, Kazimierz
Zwierzchowski, Lech
NEUROENDOCRINOLOGY LETTERS, 2008, 29 (06) : 981 - 989
[10] ASSOCIATIONS OF SIX SNPS OF POU1F1-PROP1-PITX1-SIX3 PATHWAY GENES WITH GROWTH TRAITS IN TWO CHINESE INDIGENOUS GOAT BREEDS
Ma, Lin
Qin, Qiaomei
Yang, Qing
Zhang, Meng
Zhao, Haiyu
Pan, Chuanying
Lei, Chuzhao
Chen, Hong
Lan, Xianyong
ANNALS OF ANIMAL SCIENCE, 2017, 17 (02): : 399 - 411

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