Genomic analysis of a novel spontaneous albino C57BL/6N mouse strain

被引：3

作者：

Ryder, Edward ^{[1
]}

Wong, Kim ^{[1
]}

Gleeson, Diane ^{[1
]}

Keane, Thomas M. ^{[1
]}

Sethi, Debarati ^{[1
]}

Vyas, Sapna ^{[1
]}

Wardle-Jones, Hannah ^{[1
]}

Bussell, James N. ^{[1
]}

Houghton, Richard ^{[1
]}

Salisbury, Jennifer ^{[1
]}

Harvey, Nina ^{[1
]}

Adams, David J. ^{[1
]}

Ramirez-Solis, Ramiro ^{[1
]}

机构：

[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, Cambs, England

来源：

GENESIS | 2013年 / 51卷 / 07期

基金：

英国惠康基金;

关键词：

mouse; genome sequencing; genetics; transgenics; mammalian; genomics; RESOURCE;

D O I：

10.1002/dvg.22398

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We report an albino C57BL/6N mouse strain carrying a spontaneous mutation in the tyrosinase gene (C57BL/6N-Tyr(cWTSI)). Deep whole genome sequencing of founder mice revealed very little divergence from C57BL/6NJ and C57BL/6N (Taconic). This coisogenic strain will be of great utility for the International Mouse Phenotyping Consortium (IMPC), which uses the EUCOMM/KOMP targeted C57BL/6N ES cell resource, and other investigators wishing to work on a defined C57BL/6N background. genesis 51:523-528. (c) 2013 Wiley Periodicals, Inc.

引用

页码：523 / 528

页数：6

共 18 条

[1] The mammalian gene function resource: the international knockout mouse consortium [J].

Bradley, Allan ;

Anastassiadis, Konstantinos ;

Ayadi, Abdelkader ;

Battey, James F. ;

Bell, Cindy ;

Birling, Marie-Christine ;

Bottomley, Joanna ;

Brown, Steve D. ;

Buerger, Antje ;

Bult, Carol J. ;

Bushell, Wendy ;

Collins, Francis S. ;

Desaintes, Christian ;

Doe, Brendan ;

Economides, Aris ;

Eppig, Janan T. ;

Finnell, Richard H. ;

Fletcher, Colin ;

Fray, Martin ;

Frendewey, David ;

Friedel, Roland H. ;

Grosveld, Frank G. ;

Hansen, Jens ;

Herault, Yann ;

Hicks, Geoffrey ;

Hoerlein, Andreas ;

Houghton, Richard ;

de Angelis, Martin Hrabe ;

Huylebroeck, Danny ;

Iyer, Vivek ;

de Jong, Pieter J. ;

Kadin, James A. ;

Kaloff, Cornelia ;

Kennedy, Karen ;

Koutsourakis, Manousos ;

Lloyd, K. C. Kent ;

Marschall, Susan ;

Mason, Jeremy ;

McKerlie, Colin ;

McLeod, Michael P. ;

von Melchner, Harald ;

Moore, Mark ;

Mujica, Alejandro O. ;

Nagy, Andras ;

Nefedov, Mikhail ;

Nutter, Lauryl M. ;

Pavlovic, Guillaume ;

Peterson, Jane L. ;

Pollock, Jonathan ;

Ramirez-Solis, Ramiro .

MAMMALIAN GENOME, 2012, 23 (9-10) :580-586

[2] The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping [J].

Brown, Steve D. M. ;

Moore, Mark W. .

MAMMALIAN GENOME, 2012, 23 (9-10) :632-640

[3] Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse [J].

Church, Deanna M. ;

Goodstadt, Leo ;

Hillier, LaDeana W. ;

Zody, Michael C. ;

Goldstein, Steve ;

She, Xinwe ;

Bult, Carol J. ;

Agarwala, Richa ;

Cherry, Joshua L. ;

DiCuccio, Michael ;

Hlavina, Wratko ;

Kapustin, Yuri ;

Meric, Peter ;

Maglott, Donna ;

Birtle, Zoe ;

Marques, Ana C. ;

Graves, Tina ;

Zhou, Shiguo ;

Teague, Brian ;

Potamousis, Konstantinos ;

Churas, Christopher ;

Place, Michael ;

Herschleb, Jill ;

Runnheim, Ron ;

Forrest, Daniel ;

Amos-Landgraf, James ;

Schwartz, David C. ;

Cheng, Ze ;

Lindblad-Toh, Kerstin ;

Eichler, Evan E. ;

Ponting, Chris P. .

PLOS BIOLOGY, 2009, 7 (05)

[4]

Gabriel S, 2009, CURR PROTOCOLS HUM G, V60, P2121

[5] PCRTiler: automated design of tiled and specific PCR primer pairs [J].

Gervais, Alain L. ;

Marques, Maud ;

Gaudreau, Luc .

NUCLEIC ACIDS RESEARCH, 2010, 38 :W308-W312

[6] Mouse genomic variation and its effect on phenotypes and gene regulation [J].

Keane, Thomas M. ;

Goodstadt, Leo ;

Danecek, Petr ;

White, Michael A. ;

Wong, Kim ;

Yalcin, Binnaz ;

Heger, Andreas ;

Agam, Avigail ;

Slater, Guy ;

Goodson, Martin ;

Furlotte, Nicholas A. ;

Eskin, Eleazar ;

Nellaker, Christoffer ;

Whitley, Helen ;

Cleak, James ;

Janowitz, Deborah ;

Hernandez-Pliego, Polinka ;

Edwards, Andrew ;

Belgard, T. Grant ;

Oliver, Peter L. ;

McIntyre, Rebecca E. ;

Bhomra, Amarjit ;

Nicod, Jerome ;

Gan, Xiangchao ;

Yuan, Wei ;

van der Weyden, Louise ;

Steward, Charles A. ;

Bala, Sendu ;

Stalker, Jim ;

Mott, Richard ;

Durbin, Richard ;

Jackson, Ian J. ;

Czechanski, Anne ;

Guerra-Assuncao, Jose Afonso ;

Donahue, Leah Rae ;

Reinholdt, Laura G. ;

Payseur, Bret A. ;

Ponting, Chris P. ;

Birney, Ewan ;

Flint, Jonathan ;

Adams, David J. .

NATURE, 2011, 477 (7364) :289-294

[7] THE MOUSE TYROSINASE PROMOTER IS SUFFICIENT FOR EXPRESSION IN MELANOCYTES AND IN THE PIGMENTED EPITHELIUM OF THE RETINA [J].

KLUPPEL, M ;

BEERMANN, F ;

RUPPERT, S ;

SCHMID, E ;

HUMMLER, E ;

SCHUTZ, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (09) :3777-3781

[8] A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data [J].

Li, Heng .

BIOINFORMATICS, 2011, 27 (21) :2987-2993

[9]

Li H, 2009, BIOINFORMATICS, V25, P1094, DOI [10.1093/bioinformatics/btp324, 10.1093/bioinformatics/btp100]

[10]

Liu PT, 1998, GENETICS, V150, P1155

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