Comparison of resazurin microtiter assay performance and BACTEC MGIT 960 in the susceptibility testing of Brazilian clinical isolates of Mycobacterium tuberculosis to four first-line drugs

被引:10
作者
Miyata, Marcelo [1 ]
Pavan, Fernando Rogerio [1 ]
Sato, Daisy Nakamura [1 ]
Marino, Leonardo Biancolino [1 ]
Hirata, Mario Hiroyuki [2 ]
Cardoso, Rosilene Fressati [3 ]
Fiuza de Melo, Fernando Augusto [4 ]
Fujimura Leite, Clarice Queico [1 ]
机构
[1] Univ Estadual Paulista, Fac Ciencias Farmaceut, Araraquara, SP, Brazil
[2] Univ Sao Paulo, Fac Ciencias Farmaceut, Sao Paulo, Brazil
[3] Univ Estadual Maringa, Dept Anal Clin & Biomed, Maringa, Parana, Brazil
[4] Inst Clemente Ferreira, Sao Paulo, Brazil
基金
巴西圣保罗研究基金会;
关键词
Mycobacterium tuberculosis; tuberculosis; drug susceptibility testing; RESISTANCE; MUTATIONS; AVIUM;
D O I
10.1590/S1517-83822013005000028
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We assessed the performance of REMA in comparison with BACTEC MGIT 960 in the susceptibility testing of 80 Mycobacterium tuberculosis clinical isolates from Clemente Ferreira Institute against four drugs. REMA proved to be a rapid and accurate method, providing excellent correlation with BACTEC MGIT 960, with the exception of results for the ethambutol drug.
引用
收藏
页码:281 / 285
页数:5
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