Myocardial Late Iodine Enhancement and Extracellular Volume Quantification with DualLayer Spectral Detector Dual-Energy Cardiac CT

被引：69

作者：

Oda, Seitaro ^{[1
]}

Emoto, Takafumi ^{[5
]}

Nakaura, Takeshi ^{[1
]}

Kidoh, Masafumi ^{[1
]}

Utsunomiya, Daisuke ^{[1
]}

Funama, Yoshinori ^{[2
]}

Nagayama, Yasunori ^{[1
]}

Takashio, Seiji ^{[3
]}

Ueda, Mitsuharu ^{[4
]}

Yamashita, Taro ^{[4
]}

Tsujita, Kenichi ^{[3
]}

Ando, Yukio ^{[4
]}

Yamashita, Yasuyuki ^{[1
]}

机构：

[1] Kumamoto Univ, Fac Life Sci, Dept Diagnost Radiol, Chuo Ku, 1-1-1 Honiyo, Kumamoto 8608556, Japan

[2] Kumamoto Univ, Fac Life Sci, Dept Med Phys, Chuo Ku, 1-1-1 Honiyo, Kumamoto 8608556, Japan

[3] Kumamoto Univ, Fac Life Sci, Dept Cardiol, Chuo Ku, 1-1-1 Honiyo, Kumamoto 8608556, Japan

[4] Kumamoto Univ, Fac Life Sci, Dept Neurol, Chuo Ku, 1-1-1 Honiyo, Kumamoto 8608556, Japan

[5] Kumamoto Univ Hosp, Dept Cent Radiol, Kumamoto, Japan

来源：

RADIOLOGY-CARDIOTHORACIC IMAGING | 2019年 / 1卷 / 01期

关键词：

VIRTUAL MONOENERGETIC IMAGES; COMPUTED-TOMOGRAPHY; DELAYED ENHANCEMENT; DIAGNOSTIC-ACCURACY; MAGNETIC-RESONANCE; MULTIDETECTOR CT; IN-VITRO; ALGORITHM; FRACTION; NOISE;

D O I：

10.1148/ryct.2019180003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: To explore the usefulness of myocardial late iodine enhancement (LIE) and extracellular volume (ECV) quantification by using dual-energy cardiac CT. Materials and Methods: In this single-center retrospective study, a total of 40 patients were evaluated with LIE CT by using a duallayer spectral detector CT system. Among these, 21 also underwent cardiac MRI. Paired image sets were created by using standard imaging at 120 kVp, virtual monochromatic imaging (VMI) at 50 keV, and iodine density imaging. The contrast-to-noise ratio and image quality were then compared. Two observers assessed the presence of LIE and calculated the interobserver agreements. Agreement between CT and cardiac MRI when detecting late-enhancing lesions and calculating the ECV was also assessed. Results: The contrast-to-noise ratio was significantly higher by using VMI than by using standard 120-kVp imaging, and the mean visual image quality score was significantly higher by using VMI than by using either standard or iodine density imaging. For interobserver agreement of visual detection of LIE, the agreement for VMI was excellent and the k value (k, 0.87) was higher than that for the standard 120-kVp (k, 0.70) and iodine density (k, 0.83) imaging. For detecting late-enhancing lesions, agreement with cardiac MRI was excellent by using VMI (k, 0.90) and iodine density imaging (k, 0.87) but was only good by using standard 120-kVp imaging (k, 0.66). Quantitative comparisons of the ECV calculations by using CT and cardiac MRI showed excellent correlation (r2 = 0.94). Conclusion: Dual-energy cardiac CT can assess myocardial LIE and quantify ECV, with results comparable to those obtained by using cardiac MRI.

引用

页数：10

共 39 条

[1] Advanced image-based virtual monoenergetic dual-energy CT angiography of the abdomen: optimization of kiloelectron volt settings to improve image contrast [J].