Middle East respiratory syndrome coronavirus (MERS-CoV): A cluster analysis with implications for global management of suspected cases

被引：27

作者：

Memish, Ziad A. ^{[1
,2
]}

Al-Tawfiq, Jaffar A. ^{[3
,4
]}

Alhakeem, Rafat F. ^{[1
]}

Assiri, Abdullah ^{[1
]}

Alharby, Khalid D. ^{[5
]}

Almahallawi, Maher S. ^{[5
]}

Alkhallawi, Mohammed ^{[5
]}

机构：

[1] Minist Hlth, Riyadh, Saudi Arabia

[2] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia

[3] Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia

[4] Indiana Univ Sch Med, Indianapolis, IN 46202 USA

[5] Minist Hlth, Reg Hlth Directorate, Madinah, Saudi Arabia

来源：

TRAVEL MEDICINE AND INFECTIOUS DISEASE | 2015年 / 13卷 / 04期

关键词：

Middle East; Clusters; MERS-CoV; RT-PCR; Coronavirus; NASAL CARRIAGE; SAUDI-ARABIA; 2013; HAJJ; PILGRIMS; SURVEILLANCE; INFECTIONS; OUTBREAK; JEDDAH;

D O I：

10.1016/j.tmaid.2015.06.012

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Since the initial description of the Middle East respiratory syndrome (MERS) in September 2012, a total of 1038 cases of MERS-CoV including 460 deaths have been reported from Saudi Arabia. From August 24, 2013 to September 3, 2013, a total of 397 patients and contacts were tested for MERS-CoV. Of those tested, there were 18 (4.5%) MERS-CoV cases reported in Al-Madinah al-Munawwarah with one large cluster. In this report, we describe the outcome, epidemiology and clinical characteristics of this cluster of which 4 cases involved healthcare workers. Fourteen cases appeared to be linked to one cluster involving healthcare workers (HCWs), family and patient contacts. Of the 18 cases, five (including 2 HCWs) were community acquired, two were household contacts, and 11 were healthcare associated (including 4 HCWs). All except 4 cases were symptomatic and the case fatality rate was 39% (7 of 18). The outbreak resulted in human to human transmission of an estimated 6 cases. Contact screening showed positive test in 1 of 56 (1.8%) household contacts, and 3 of 250 (1.2%) HCWs. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：311 / 314

页数：4

共 22 条

[21] Imported cases of Middle East respiratory syndrome: An update [J].

Sridhar, Shruti ;

Brouqui, Philippe ;

Parola, Philippe ;

Gautret, Philippe .

TRAVEL MEDICINE AND INFECTIOUS DISEASE, 2015, 13 (01) :106-109

[22] The Hajj pilgrimage and surveillance for Middle East Respiratory syndrome coronavirus in pilgrims from African countries [J].

Zumla, Alimuddin ;

Mwaba, Peter ;

Bates, Matthew ;

Al-Tawfiq, Jaffar A. ;

Maeurer, Markus ;

Memish, Ziad A. .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2014, 19 (07) :838-840

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