Single and Dual Pathologies of the Temporal Lobe: Effects on Cognitive Function in Children with Epilepsy

被引:16
|
作者
Bigel, Marla G. [2 ]
Smith, Mary Lou [1 ,2 ]
机构
[1] Univ Toronto, Dept Psychol, Mississauga, ON L5L 1C6, Canada
[2] Hosp Sick Children, Dept Psychol, Toronto, ON M5G 1X8, Canada
关键词
temporal lobe epilepsy; children; neuropathology; neuropsychology; hippocampal sclerosis; tumor; cortical dysplasia; cognition;
D O I
10.1006/ebeh.2000.0146
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
The neuropathologies associated with temporal lobe epilepsy (TLE) are heterogeneous. The performance of 61 children with single pathology of hippocampal sclerosis (HS), temporal lobe tumor, or cortical dysplasia (CD) or dual pathology of HS + tumor or HS + CD was examined on measures of intelligence, language, memory, and executive function. Children with single pathologies performed significantly better than did children with HS + CD on all standardized measures of IQ. Children with tumors performed significantly better than children with dual pathology on receptive vocabulary. These results support prior research of an association between neuropathology and cognitive function in children with epilepsy and extend the findings to include additional neuropathologies and measures of cognitive functioning. (C) 2001 Academic Press
引用
收藏
页码:37 / 45
页数:9
相关论文
共 50 条
  • [31] Effect of donepezil and memantine on improvement of cognitive function in patients with temporal lobe epilepsy
    Oustad, Marjan
    Najafi, Mohamadreza
    Mehvari, Jafar
    Rastgoo, Amin
    Mortazavi, Zahrasadat
    Rahiminejad, Mitre
    JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2020, 25
  • [32] Metabolic correlates of cognitive impairment in mesial temporal lobe epilepsy
    Laurent, Agathe
    Artiges, Eric
    Mellerio, Charles
    Boutin-Watine, Magali
    Landre, Elisabeth
    Semah, Franck
    Chassoux, Francine
    EPILEPSY & BEHAVIOR, 2020, 105
  • [33] Benzyl isothiocyanate ameliorates cognitive function in mice of chronic temporal lobe epilepsy
    Chang, Xiaoyu
    Zhou, Hongzhen
    Peng, Nan
    Gao, Tengwei
    Gong, Yanan
    Guo, Yan
    La, Haiyan
    Ma, Li
    Wu, Haiya
    Wen, Yujun
    Zhang, Rui
    FRONTIERS IN NEUROLOGY, 2024, 15
  • [34] Temporal lobe epilepsy and focal cortical dysplasia in children: A tip to find the abnormality
    Bartolini, Luca
    Whitehead, Matthew T.
    Ho, Cheng-Ying
    Sepeta, Leigh N.
    Oluigbo, Chima O.
    Havens, Kathryn
    Freilich, Emily R.
    Schreiber, John M.
    Gaillard, William D.
    EPILEPSIA, 2017, 58 (01) : 113 - 122
  • [35] Nonlinear Trends in Hippocampal Metabolic Function and Verbal Memory: Evidence of Cognitive Reserve in Temporal Lobe Epilepsy?
    Sawrie, Stephen M.
    Martin, Roy C.
    Faught, R. Edward
    Maton, Bruno
    Hugg, James W.
    Kuzniecky, Ruben I.
    EPILEPSY & BEHAVIOR, 2000, 1 (02) : 106 - 111
  • [36] Interictal epileptic discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy
    Dinkelacker, Vera
    Xin, Xu
    Baulac, Michel
    Samson, Severine
    Dupont, Sophie
    EPILEPSY & BEHAVIOR, 2016, 62 : 197 - 203
  • [37] Systematic Review of Cognitive Function in euthymic Bipolar Disorder and Pre-Surgical Temporal Lobe epilepsy
    Bostock, Emmanuelle C. S.
    Kirkby, Kenneth C.
    Garry, Michael I.
    Taylor, Bruce V. M.
    FRONTIERS IN PSYCHIATRY, 2017, 8
  • [38] Neuropsychological evaluation in children with epilepsy: attention and executive functions in temporal lobe epilepsy
    Lopes, Ana F. D.
    Simoes, Mario M. R.
    Robalo, Conceicao N.
    Fineza, Isabel
    Goncalves, Olavo B.
    REVISTA DE NEUROLOGIA, 2010, 50 (05) : 265 - 272
  • [39] Optimizing memory function in temporal lobe epilepsy
    Thompson, P. J.
    Conn, H.
    Baxendale, S. A.
    Donnachie, E.
    McGrath, K.
    Geraldi, C.
    Duncan, J. S.
    SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2016, 38 : 68 - 74
  • [40] Wisconsin card sorting test in children with temporal lobe epilepsy
    Igarashi, K
    Oguni, H
    Osawa, M
    Awaya, Y
    Kato, M
    Mimura, M
    Kashima, H
    BRAIN & DEVELOPMENT, 2002, 24 (03) : 174 - 178