Comparison of left atrial volumes and function by real-time three-dimensional echocardiography in patients having catheter ablation for atrial fibrillation with persistence of sinus rhythm versus recurrent atrial fibrillation three months later

被引：100

作者：

Marsan, Nina Ajmone ^{[1
,2
]}

Tops, Laurens F. ^{[1
]}

Holman, Eduard R. ^{[1
]}

Van de Veire, Nico R. ^{[3
]}

Zeppenfeld, Katja ^{[1
]}

Boersma, Eric ^{[4
]}

van der Wall, Ernst E. ^{[1
,5
]}

Schalij, Martin J. ^{[1
]}

Bax, Jeroen J. ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands

[2] Policlin San Matteo, IRCCS, I-27100 Pavia, Italy

[3] Univ Ghent, B-9000 Ghent, Belgium

[4] Erasmus Univ, Dept Epidemiol & Stat, Rotterdam, Netherlands

[5] Interuniv Cardiol Inst Netherlands, Utrecht, Netherlands

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2008年 / 102卷 / 07期

关键词：

D O I：

10.1016/j.amjcard.2008.05.048

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Real-time 3-dimensional echocardiography (RT3DE) can provide a unique combination of accurate left atrial (LA) volume quantification and rapid, automatic assessment of LA function. The aim of the study was to evaluate the changes in LA volumes and function in patients with atrial fibrillation (AF) undergoing radiofrequency catheter ablation (RFCA) using RT3DE; 57 consecutive patients referred for RFCA were studied. Paroxysmal AF was present in 43 patients (75%) and persistent AF in 14 (25%). After a mean follow-up of 7.9 +/- 2.7 months, patients were divided into 2 groups: successful RFCA (SR group) and recurrence of AF (AF group). RT3DE was performed before, within 3 days, and 3 months after RFCA to assess LA volumes (maximum, minimum, and preA) and LA functions (passive, active, and reservoir). A total of 38 patients (67%) had successful RFCA (SR group). Immediately after RFCA, no significant changes in LA volumes and function were observed. After 3 months, a significant reduction in LA volumes (maximum: 26 +/- 8 to 23 +/- 7 ml/m(2), P <0.01) was noted only in the SR group, with a significant improvement in LA active (22 +/- 8% to 33 +/- 9%, p <0.01) and reservoir functions (116 +/- 45% to 152 +/- 54%, p <0.01). Conversely, the AF group showed a trend towards a deterioration of LA volumes and function. In conclusion, in patients who maintain sinus rhythm after RFCA, a significant reverse remodeling and functional improvement of the left atrium is observed using RT3DE. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：847 / 853

页数：7

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