Photodynamic therapy in superficial bladder cancer: past, present and future

被引：55
作者：
Jichlinski, P [1 ]
Leisinger, HJ [1 ]
机构：
[1] CHU Vaudois, Univ Hosp, Dept Urol, CH-1011 Lausanne, Switzerland
来源：
UROLOGICAL RESEARCH | 2001年 / 29卷 / 06期
关键词：
bladder cancer; photodynamic therapy; dihaematoporphyrin derivatives; protoporphyrin IX; 5-aminolevulinic acid; hexyl-ester of aminolevulinic acid; hypericin;
D O I：
10.1007/s002400100215
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
For many reasons, such as toxicity and lack of selectivity of photosensitisers, as well as complexity of technical procedures and inconstant therapeutic results, photodynamic therapy of highly recurrent superficial bladder cancer never gained wide acceptance in the urological community. However, the 25 years of experience combined with the recent discovery of new photosensitisers, such as protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (ALA) or ALA-derivatives or hypericin open new, very interesting perspectives in this therapeutic field.
引用
收藏
页码：396 / 405
页数：10
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