Intracerebral small round cell tumor: An unusual case with EWS-WT1 translocation

被引：11

作者：

Bouchireb, Karim ^{[1
]}

Auger, Nathalie ^{[2
]}

Bhangoo, Ranjeev ^{[3
]}

Di Rocco, Federico ^{[4
]}

Brousse, Nicole ^{[5
]}

Delattre, Olivier ^{[6
]}

Varlet, Pascale ^{[7
]}

Grill, Jacques ^{[3
]}

机构：

[1] Inst Gustave Roussy, Dept Pediat & Adolescent Oncol, Villejuif, France

[2] Inst Gustave Roussy, Dept Biol Clin, F-94805 Villejuif, France

[3] Univ Paris 11, UPRES EA Pharmacol & New Treatments Canc 3535, Inst Gustave Roussy, Villejuif, France

[4] Hop Necker Enfants Malad, Dept Neurosurg, Paris, France

[5] Hop Necker Enfants Malad, Dept Anat Pathol, Ctr Resources Biol, Paris, France

[6] Inst Curie, Lab Pathol Mol Canc, Paris, France

[7] Ctr Hosp St Anne, Neuropathol Lab, Paris, France

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 51卷 / 04期

关键词：

brain; desmoplastic small round cell tumor; EWS-WT1; translocation;

D O I：

10.1002/pbc.21648

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Desmplastic small round cell tumor (DSRCT) is rare tumor, seen both in children and young adults with a marked predilection for the peritoneal cavity. Histology showed a small round cell tumor with a fibromyxoid stroma and immunohistochemistry indicated neural and mesenchymal differentiation, and diagnosis was made by molecular detection of the EWS-WT1 fusion gene product. DSRCT should be considered in the differential diagnosis of intracranial small round cell tumors.

引用

页码：545 / 548

页数：4

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