New anti-inflammatory 4-methylated steroids from the Formosan soft coral Nephthea chabroli

被引：30
|
作者：
Huang, Ya-Ching [1 ]
Wen, Zhi-Hong [1 ]
Wang, Shang-Kwei [2 ]
Hsu, Chi-Hsin [1 ]
Duh, Chang-Yih [1 ]
机构：
[1] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Ctr Asia Pacific Marine Res, Kaohsiung 80424, Taiwan
[2] Kaohsiung Med Univ, Dept Microbiol, Kaohsiung, Taiwan
来源：
STEROIDS | 2008年 / 73卷 / 11期
关键词：
4-methylated steroids; Nephthea chabroli; anti-inflammatory activity;
D O I：
10.1016/j.steroids.2008.05.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Eight new 4-methylated steroids, nebrosteroids A-H (1-8) were isolated from the acetone solubles of the Formosan soft coral Nephthea chabroli. The structures were elucidated by extensive NMR spectroscopic analysis and their anti-inflammatory activity was measured in vitro. (c) 2003 Elsevier Inc. All rights reserved.
引用
收藏
页码：1181 / 1186
页数：6
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