Cytotoxic acridone alkaloids from the stem bark of Citrus maxima

被引：13

作者：

Teng, WY

Huang, YL

Shen, CC

Huang, RL

Chung, RS ^{[1
]}

Chen, CC

机构：

[1] Natl Taiwan Univ, Dept Agr Chem, Taipei 10764, Taiwan

[2] Natl Res Inst Chinese Med, Taipei, Taiwan

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2005年 / 52卷 / 06期

关键词：

Citrus maxima; stem bark; aqueous portion; acridone alkaloid; anti-tumor activity;

D O I：

10.1002/jccs.200500180

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new acridone alkaloid, 5-hydroxynoracronycine alcohol (4), along with six known acridone alkaloids, glycocitrine-I (1), 5-hydroxyiloracronycine (2), citrusinine-I (3), grandisine-I (5), natsucitrine-II (6), and citracridone-III (7), were isolated from the stem bark of Citrus maxima f. buntan. Their Structures were established on the basis of spectroscopic methods. Compounds 1-4 and 7 were found to be cytotoxic on two tumor cell lines.

引用

页码：1253 / 1255

页数：3

共 19 条

[1]

CARMICHAEL J, 1987, CANCER RES, V47, P936

[2] INHIBITION OF CELL-GROWTH AND MACROMOLECULE BIOSYNTHESIS OF HUMAN PROMYELOCYTIC LEUKEMIC-CELLS BY ACRIDONE ALKALOIDS [J].