Cytotoxic acridone alkaloids from the stem bark of Citrus maxima

被引:13
作者
Teng, WY
Huang, YL
Shen, CC
Huang, RL
Chung, RS [1 ]
Chen, CC
机构
[1] Natl Taiwan Univ, Dept Agr Chem, Taipei 10764, Taiwan
[2] Natl Res Inst Chinese Med, Taipei, Taiwan
关键词
Citrus maxima; stem bark; aqueous portion; acridone alkaloid; anti-tumor activity;
D O I
10.1002/jccs.200500180
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new acridone alkaloid, 5-hydroxynoracronycine alcohol (4), along with six known acridone alkaloids, glycocitrine-I (1), 5-hydroxyiloracronycine (2), citrusinine-I (3), grandisine-I (5), natsucitrine-II (6), and citracridone-III (7), were isolated from the stem bark of Citrus maxima f. buntan. Their Structures were established on the basis of spectroscopic methods. Compounds 1-4 and 7 were found to be cytotoxic on two tumor cell lines.
引用
收藏
页码:1253 / 1255
页数:3
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