Comparison of radiotherapy strategies for locally advanced hypopharyngeal cancer after resection and ileocolic flap reconstruction

被引：12

作者：

Tai, Hung-Chi ^{[1
]}

Hsieh, Chen-Hsi ^{[1
,9
]}

Chao, K. Clifford ^{[10
]}

Liu, Shih-Hua ^{[1
]}

Leu, Yi-Shing ^{[2
]}

Chang, Yih-Fang ^{[3
]}

Hsiao, Hung-Tao ^{[4
]}

Chang, Yuan-Ching ^{[5
]}

Huang, David Y. C. ^{[6
]}

Chen, Yu-Jen ^{[1
,7
,8
]}

机构：

[1] Mackay Mem Hosp, Dept Radiat Oncol, Taipei 104, Taiwan

[2] Mackay Mem Hosp, Dept Otolaryngol, Taipei 104, Taiwan

[3] Mackay Mem Hosp, Dept Hematol, Taipei 104, Taiwan

[4] Mackay Mem Hosp, Dept Plast Surg, Taipei 104, Taiwan

[5] Mackay Mem Hosp, Dept Gen Surg, Taipei 104, Taiwan

[6] Mem Sloan Kettering Canc Ctr, Dept Med Phys, New York, NY 10021 USA

[7] Chinese Culture Univ, Grad Inst Sport Coaching Sci, Taipei, Taiwan

[8] Natl Yang Ming Univ, Taiwan Inst Tradit Med, Taipei 112, Taiwan

[9] Far Eastern Mem Hosp, Dept Radiat Oncol, Taipei, Taiwan

[10] Univ Texas Houston, MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA

来源：

ACTA OTO-LARYNGOLOGICA | 2009年 / 129卷 / 03期

关键词：

Hypopharyngeal cancer; intensity modulated radiation therapy; 3D conformal radiotherapy; ileocolic flap; MODULATED RADIATION-THERAPY; NECK CANCERS; HEAD; IMRT; CARCINOMA;

D O I：

10.1080/00016480802163366

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Conclusion. IMRT provided better conformity, less toxicity and better function restoration for advanced hypopharyngeal carcinoma after major surgery with ileocolic flap reconstruction. Objectives. To compare the results of adjuvant conventional radiotherapy (2DRT) with intensity modulated radiation therapy (IMRT) for locally advanced hypopharyngeal cancer after resection and ileocolic free flap reconstruction and to design treatment plans for those two modalities plus 3D conformal radiotherapy (3DCRT) for dose distribution comparison. Methods. 13 locally advanced hypopharyngeal cancer patients were enrolled, 8 treated with 2DRT and 5 with IMRT. Different plans were planned for 3 IMRT-treated patients for comparing dose distribution. Results. After major surgery, patients treated with IMRT had less toxicity and better functional restoration than those with 2DRT. IMRT and 3DCRT both showed lower dose to the spinal cord than did 2DRT. Only IMRT showed reduced dose to ileocolic flap.

引用

页码：311 / 317

页数：7

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