Ginsenosides from Heat Processed Ginseng

被引:56
|
作者
Lee, Sang Myung [2 ]
Shon, Hyun Ju [2 ]
Choi, Chung-Sig [1 ]
Hung, Tran Manh [1 ]
Min, Byung Sun [1 ]
Bae, KiHwan [3 ]
机构
[1] Catholic Univ Daegu, Coll Pharm, Gyeongbuk 712702, South Korea
[2] KT&G Cent Res Inst, Taejon 305805, South Korea
[3] Chungnam Natl Univ, Coll Pharm, Taejon 305764, South Korea
关键词
Panax ginseng; heat treatment; ginsenoside Rz(1); HPLC; DAMMARANE GLYCOSIDES; SAPONINS;
D O I
10.1248/cpb.57.92
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new dammarane-glycoside, ginsenoside Rz(1) (1), was isolated from heat-treated Panax ginseng C. A. MEYER (Araliaceae) with ginsenosides Rk(1) and Rg(5). The structure of 1 was established to be (Z)-12 beta-hydroxydammara-20(22),24-dien-3 beta-yl O-beta-D-glucopyranosyl-(1 -> 2)-beta-D-glucospyranoside by spectroscopic means. HPLC analyses revealed that the ginsenosides Rz(1) Rk(1) and Rg(5) were present in the ratios of 1 :2: 6, respectively.
引用
收藏
页码:92 / 94
页数:3
相关论文
共 50 条
  • [1] Cyclooxygenase inhibitory activity of ginsenosides from heat-processed ginseng
    Yoo, Hye Hyun
    Park, Jeong Hill
    FOOD CHEMISTRY, 2012, 133 (03) : 998 - 1000
  • [2] Three New Ginsenosides from the Heat-Processed Roots of Panax ginseng
    Jin-Gyeong Cho
    Dae-Young Lee
    Sabina Shrestha
    Sang-Kap Lee
    Hyun-Mi Kang
    Sung-Ho Son
    Deok-Chun Yang
    Nam-In Baek
    Chemistry of Natural Compounds, 2013, 49 : 882 - 887
  • [3] Three New Ginsenosides from the Heat-Processed Roots of Panax ginseng
    Cho, Jin-Gyeong
    Lee, Dae-Young
    Shrestha, Sabina
    Lee, Sang-Kap
    Kang, Hyun-Mi
    Son, Sung-Ho
    Yang, Deok-Chun
    Baek, Nam-In
    CHEMISTRY OF NATURAL COMPOUNDS, 2013, 49 (05) : 882 - 887
  • [4] Four new acetylated ginsenosides from processed ginseng (sun ginseng)
    Il Ho Park
    Sang Beom Han
    Jong Moon Kim
    Longzhu Piao
    Sung Won Kwon
    Na Young Kim
    Tak Lim Kang
    Man Ki Park
    Jeong Hill Park
    Archives of Pharmacal Research, 2002, 25 : 837 - 841
  • [5] Four new acetylated ginsenosides from processed ginseng (sun ginseng)
    Park, IH
    Han, SB
    Kim, JM
    Piao, LZ
    Kwon, SW
    Kim, NY
    Kang, TL
    Park, MK
    Park, JH
    ARCHIVES OF PHARMACAL RESEARCH, 2002, 25 (06) : 837 - 841
  • [7] Anti-complementary Ginsenosides Isolated from Processed Ginseng
    Lee, Jin Gyun
    Baek, Seung Hoon
    Lee, Yong Yook
    Park, Seo Young
    Park, Jeong Hill
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2011, 34 (06) : 898 - 900
  • [8] Platelet antiaggregating activity of ginsenosides isolated from processed ginseng
    Lee, Jin Gyun
    Lee, Yong Yook
    Kim, Sun Young
    Pyo, Jae Sung
    Yun-Choi, Hye Sook
    Park, Jeong Hill
    PHARMAZIE, 2009, 64 (09): : 602 - 604
  • [9] Inhibitory activity of ginsenosides isolated from processed ginseng on platelet aggregation
    Lee, Jin Gyun
    Lee, Yong Yook
    Wu, Bo
    Kim, Sun Young
    Lee, Yong Jae
    Yun-Choi, Hye Sook
    Park, Jeong Hill
    PHARMAZIE, 2010, 65 (07): : 520 - 522
  • [10] Liquid chromatographic determination of less polar ginsenosides in processed ginseng
    Kwon, SW
    Han, SB
    Park, IH
    Kim, JM
    Park, MK
    Park, JH
    JOURNAL OF CHROMATOGRAPHY A, 2001, 921 (02) : 335 - 339