Synthesis of analogues of 5'-mono-, 5'-di-, and 5'-triphosphate-AZT for the development of specific enzyme immunoassay for monitoring of intracellular levels of AZT-MP, AZT-DP, and AZT-TP.

被引:3
作者
Brossette, T
Nevers, MC
Creminon, C
Mioskowski, C
Grassi, J
Lebeau, L
机构
[1] Univ Strasbourg 1, Fac Pharm, CNRS, Lab Synthese Bioorgan Associe, F-67401 Illkirch Graffenstaden, France
[2] CEA Saclay, Dept Rech Med, Serv Pharmacol & Immunol, CEA, F-91191 Gif Sur Yvette, France
来源
NUCLEOSIDES & NUCLEOTIDES | 1999年 / 18卷 / 4-5期
关键词
D O I
10.1080/15257779908041604
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The synthesis of analogue compounds of polyphosphorylated AZT is described. The compounds are designed to raise specific antibodies against AZT-MP, -DP and -TP in rabbits.
引用
收藏
页码:939 / 940
页数:2
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