Visual Detection of Glucose Using Conformational Switch of i-Motif DNA and Non-Crosslinking Gold Nanoparticles

被引:43
|
作者
Li, Wen [1 ,2 ]
Feng, Lingyan [1 ,2 ]
Ren, Jinsong [1 ]
Wu, Li [1 ,2 ]
Qu, Xiaogang [1 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Lab Chem Biol,Div Biol Inorgan Chem, Changchun 130022, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
关键词
biosensors; conformational switch; glucose; gold nanoparticles; i-motif DNA; RESONANCE ENERGY-TRANSFER; CARBON NANOTUBES; COLORIMETRIC DETECTION; GRAPHENE OXIDE; B-DNA; BIOSENSOR; TRANSITION; SCATTERING; PLATFORM; DEVICES;
D O I
10.1002/chem.201201914
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
i-Motif tuned: Glucose is a ubiquitous fuel for metabolic pathways; its oxidation can trigger i-motif DNA formation. Using this unique conformational switch and non-crosslinking gold nanoparticles, a label-free colorimetric glucose sensor has been developed (see illustration). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:12637 / 12642
页数:6
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