Dehydration of threonine esters during tosylation

被引：8
|
作者：
Somlai, C
Lovas, S
Forgó, P
Murphy, RF
Penke, B
机构：
[1] Univ Szeged, Dept Med Chem, H-6720 Szeged, Hungary
[2] Creighton Univ, Sch Med, Dept Biomed Sci, Omaha, NE 68178 USA
[3] Univ Szeged, Dept Organ Chem, H-6720 Szeged, Hungary
来源：
SYNTHETIC COMMUNICATIONS | 2001年 / 31卷 / 23期
关键词：
D O I：
10.1081/SCC-100107012
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Tosylation of N-alpha -protected threonine methyl-and benzyl esters was investigated. Depending on the protecting groups, the composition of the reaction mixtures showed different ratio between O-tosyl-and dehydrothreonine derivatives. The latter was formed exclusively in case of N-alpha -Fmoc-threonine benzyl ester.
引用
收藏
页码：3633 / 3640
页数：8
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