A new minor diketopiperazine from the sponge-derived fungus Simplicillium sp. YZ-11

被引：26

作者：

Yan, Bing-Fei ^{[1
,2
]}

Fang, Sheng-Tao ^{[2
]}

Li, Wen-Zuo ^{[1
]}

Liu, Su-Jing ^{[2
]}

Wang, Jian-Hua ^{[2
]}

Xia, Chuan-Hai ^{[2
]}

机构：

[1] Yantai Univ, Chem & Chem Engn Coll, Yantai 264005, Peoples R China

[2] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Biol Resources Utilizat, Yantai 264003, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 21期

基金：

中国国家自然科学基金;

关键词：

marine sponge; cyclo-(2-hydroxy-Pro-Gly); Simplicillium sp; diketopiperazine; sterols; MARINE; METABOLITES; BACTERIUM;

D O I：

10.1080/14786419.2015.1027890

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Chemical investigation of the cultures of a sponge-derived fungus Simplicillium sp. YZ-11 led to the isolation of a new minor diketopiperazine alkaloid cyclo-(2-hydroxy-Pro-Gly) (1) and a natural lactone (S)-dihydro-5-[(S)- hydroxyphenylmethyl]-2(3H)-furanone (2), together with five known ergostane-type sterols (3-7). Their structures were established based on extensive spectroscopic methods (H-1 and C-13 NMR, H-1-H-1 COSY, HSQC and HMBC) and optical rotation analysis.

引用

页码：2013 / 2017

页数：5

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