Use of Inhaled Nitric Oxide in Preterm Infants

被引:97
|
作者
Kumar, Praveen
机构
关键词
inhaled nitric oxide; preterm infants; hypoxic respiratory failure; bronchopulmonary dysplasia; RANDOMIZED CONTROLLED-TRIAL; SEVERE RESPIRATORY-FAILURE; CHRONIC LUNG-DISEASE; PREMATURE-INFANTS; NEURODEVELOPMENTAL OUTCOMES; THERAPY; GROWTH; NEWBORNS; SYNTHASE; CELLS;
D O I
10.1542/peds.2013-3444
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Nitric oxide, an important signaling molecule with multiple regulatory effects throughout the body, is an important tool for the treatment of full-term and late-preterm infants with persistent pulmonary hypertension of the newborn and hypoxemic respiratory failure. Several randomized controlled trials have evaluated its role in the management of preterm infants <= 34 weeks' gestational age with varying results. The purpose of this clinical report is to summarize the existing evidence for the use of inhaled nitric oxide in preterm infants and provide guidance regarding its use in this population.
引用
收藏
页码:164 / 170
页数:7
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