[Fe]-Hydrogenase and Models that Contain IronAcyl Ligation

被引：38

作者：

Schultz, Katherine M. ^{[1
]}

Chen, Dafa ^{[2
]}

Hu, Xile ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Chem Sci & Engn, Lab Inorgan Synth & Catalysis, SB ISIC LSCI, CH-1015 Lausanne, Switzerland

[2] Harbin Inst Technol, Sch Chem Engn & Technol, Harbin 150001, Peoples R China

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2013年 / 8卷 / 06期

基金：

中国国家自然科学基金; 瑞士国家科学基金会;

关键词：

acyl ligands; carbonyl ligands; enzymes; hydrogenase; iron; CLUSTER-FREE HYDROGENASE; ACTIVE-SITE; CRYSTAL-STRUCTURE; 3RD HYDROGENASE; H-2; ACTIVATION; INFRARED-SPECTROSCOPY; METHANOGENIC ARCHAEA; LIGHT-INACTIVATION; HMD; COMPLEX;

D O I：

10.1002/asia.201300232

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[Fe]-hydrogenase is a newly characterized type of hydrogenase. This enzyme heterolytically splits hydrogen in the presence of a natural substrate. The active site of the enzyme contains a mono-iron complex with intriguing ironacyl ligation. Several groups have recently developed ironacyl complexes as synthetic models of [Fe]-hydrogenase. This Focus Review summarizes the studies of this enzyme and its model compounds, with an emphasis on our own research in this area.

引用

页码：1068 / 1075

页数：8

共 46 条

[31]

Shima S., 2010, ANGEW CHEM, V122, P10113

[32] The crystal structure of [Fe]-hydrogenase reveals the geometry of the active site [J].

Shima, Seigo ;

Pilak, Oliver ;

Vogt, Sonja ;

Schick, Michael ;

Stagni, Marco S. ;

Meyer-Klaucke, Wolfram ;

Warkentin, Eberhard ;

Thauer, Rudolf K. ;

Ermler, Ulrich .

SCIENCE, 2008, 321 (5888) :572-575

[33] A third type of hydrogenase catalyzing H2 activation [J].

Shima, Seigo ;

Thauer, Rudolf K. .

CHEMICAL RECORD, 2007, 7 (01) :37-46

[34] Evidence for acyl-iron ligation in the active site of [Fe]-hydrogenase provided by mass spectrometry and infrared spectroscopy [J].

Shima, Seigo ;

Schick, Michael ;

Kahnt, Joerg ;

Ataka, Kenichi ;

Steinbach, Klaus ;

Linne, Uwe .

DALTON TRANSACTIONS, 2012, 41 (03) :767-771

[35] Iron-Chromophore Circular Dichroism of [Fe]-Hydrogenase: The Conformational Change Required for H2 Activation [J].

Shima, Seigo ;

Vogt, Sonja ;

Goebels, Andreas ;

Bill, Eckhard .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (51) :9917-9921

[36] Biomimetic Models for the Active Site of [Fe]Hydrogenase Featuring an Acylmethyl(hydroxymethyl)pyridine Ligand [J].

Song, Li-Cheng ;

Xie, Zhao-Jun ;

Wang, Miao-Miao ;

Zhao, Gao-Yu ;

Song, Hai-Bin .

INORGANIC CHEMISTRY, 2012, 51 (14) :7466-7468

[37] An Iron(II) Carbonyl Thiolato Complex Bearing 2-Methoxy-Pyridine: A Structural Model of the Active Site of [Fe] Hydrogenase [J].

Tanino, Soichiro ;

Ohki, Yasuhiro ;

Tatsumi, Kazuyuki .

CHEMISTRY-AN ASIAN JOURNAL, 2010, 5 (09) :1962-1964

[38] Structural and Functional Analogues of the Active Sites of the [Fe]-, [NiFe]-, and [FeFe]-Hydrogenases [J].

Tard, Cedric ;

Pickett, Christopher J. .

CHEMICAL REVIEWS, 2009, 109 (06) :2245-2274

[39] Reactions with molecular hydrogen in microorganisms: Evidence for a purely organic hydrogenation catalyst [J].

Thauer, RK ;

Klein, AR ;

Hartmann, GC .

CHEMICAL REVIEWS, 1996, 96 (07) :3031-3042

[40]

Turrell P. J., 2010, ANGEW CHEM, V122, P7670

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