Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching

被引：54

作者：

Ju, Enguo ^{[1
,2
,3
]}

Yang, Xinjian ^{[1
,2
,3
]}

Lin, Youhui ^{[1
,2
,3
]}

Pu, Fang ^{[1
,2
]}

Ren, Jinsong ^{[1
,2
]}

Qu, Xiaogang ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Jilin, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Appl Chem, Biol Chem Lab, Changchun 130022, Jilin, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 95期

基金：

中国国家自然科学基金;

关键词：

SEQUENCE-SPECIFIC DETECTION; SIGNAL AMPLIFICATION; NICKING ENDONUCLEASE; INDUCED EMISSION; POINT MUTATIONS; ASSAY; PROBE;

D O I：

10.1039/c2cc37039e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile, universal and label-free fluorescence turn-on amplification strategy for the detection of DNA has been reported, which can achieve ultralow femtomolar detection of a target gene sequence with high selectivity.

引用

页码：11662 / 11664

页数：3

共 35 条

[11] Label-free fluorescent probing of G-quadruplex formation and real-time monitoring of DNA folding by a quaternized tetraphenylethene salt with aggregation-induced emission characteristics [J].

Hong, Yuning ;

Haeussler, Matthias ;

Lam, Jacky W. Y. ;

Li, Zhen ;

Sin, King Keung ;

Dong, Yongqiang ;

Tong, Hui ;

Liu, Jianzhao ;

Qin, Anjun ;

Renneberg, Reinhard ;

Tang, Ben Zhong .

CHEMISTRY-A EUROPEAN JOURNAL, 2008, 14 (21) :6428-6437

[12] Sequence specific detection of DNA using nicking endonuclease signal amplification (NESA) [J].

Kiesling, Traci ;

Cox, Kendra ;

Davidson, Eugene A. ;

Dretchen, Kenneth ;

Grater, Guy ;

Hibbard, Shannon ;

Lasken, Roger S. ;

Leshin, Jonathan ;

Skowronski, Evan ;

Danielsen, Mark .

NUCLEIC ACIDS RESEARCH, 2007, 35 (18)

[13] Enzymatically amplified surface plasmon resonance imaging detection of DNA by exonuclease III digestion of DNA microarrays [J].

Lee, HJ ;

Li, Y ;

Wark, AW ;

Corn, RM .

ANALYTICAL CHEMISTRY, 2005, 77 (16) :5096-5100

[14] Electrochemical detection of hepatitis C virus based on site-specific DNA cleavage of BamHI endonuclease [J].

Liu, Shuna ;

Hu, Yaojuan ;

Jin, Juan ;

Zhang, Hui ;

Cai, Chenxin .

CHEMICAL COMMUNICATIONS, 2009, (13) :1635-1637

[15] A universal platform for amplified multiplexed DNA detection based on exonuclease III-coded magnetic microparticle probes [J].

Luo, Ming ;

Xiang, Xia ;

Xiang, Dongshan ;

Yang, Si ;

Ji, Xinghu ;

He, Zhike .

CHEMICAL COMMUNICATIONS, 2012, 48 (59) :7416-7418

[16] Nicking endonuclease and target recycles signal amplification assisted quantum dots for fluorescence detection of DNA [J].

Niu, Shuyan ;

Li, Quanyi ;

Qu, Lijing ;

Wang, Wei .

ANALYTICA CHIMICA ACTA, 2010, 680 (1-2) :54-58

[17] An exonuclease III and graphene oxide-aided assay for DNA detection [J].

Peng, Lu ;

Zhu, Zhi ;

Chen, Yan ;

Han, Da ;

Tan, Weihong .

BIOSENSORS & BIOELECTRONICS, 2012, 35 (01) :475-478

[18] Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis [J].

Piatek, AS ;

Tyagi, S ;

Pol, AC ;

Telenti, A ;

Miller, LP ;

Kramer, FR ;

Alland, D .

NATURE BIOTECHNOLOGY, 1998, 16 (04) :359-363

[19] Dual signal amplification for highly sensitive electrochemical detection of uropathogens via enzyme-based catalytic target recycling [J].

Su, Jiao ;

Zhang, Haijie ;

Jiang, Bingying ;

Zheng, Huzhi ;

Chai, Yaqin ;

Yuan, Ruo ;

Xiang, Yun .

BIOSENSORS & BIOELECTRONICS, 2011, 29 (01) :184-188

[20] Label-free selective sensing of mercury(II) via reduced aggregation of the perylene fluorescent probe [J].

Wang, Bin ;

Wang, Fangyuan ;

Jiao, Huping ;

Yang, Xiangyu ;

Yu, Cong .

ANALYST, 2010, 135 (08) :1986-1991

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