Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching

被引：54

作者：

Ju, Enguo ^{[1
,2
,3
]}

Yang, Xinjian ^{[1
,2
,3
]}

Lin, Youhui ^{[1
,2
,3
]}

Pu, Fang ^{[1
,2
]}

Ren, Jinsong ^{[1
,2
]}

Qu, Xiaogang ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Jilin, Peoples R China

[2] Chinese Acad Sci, Changchun Inst Appl Chem, Biol Chem Lab, Changchun 130022, Jilin, Peoples R China

[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 95期

基金：

中国国家自然科学基金;

关键词：

SEQUENCE-SPECIFIC DETECTION; SIGNAL AMPLIFICATION; NICKING ENDONUCLEASE; INDUCED EMISSION; POINT MUTATIONS; ASSAY; PROBE;

D O I：

10.1039/c2cc37039e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile, universal and label-free fluorescence turn-on amplification strategy for the detection of DNA has been reported, which can achieve ultralow femtomolar detection of a target gene sequence with high selectivity.

引用

页码：11662 / 11664

页数：3

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