Salmonella and apoptosis:: to live or let die?

被引：66
作者：
Knodler, LA
Finlay, BB
机构：
[1] Univ British Columbia, Biotechnol Lab, Vancouver, BC V6T 1Z3, Canada
[2] Univ British Columbia, Dept Microbiol & Immunol, Vancouver, BC V6T 1Z3, Canada
来源：
MICROBES AND INFECTION | 2001年 / 3卷 / 14-15期
基金：
加拿大健康研究院; 英国医学研究理事会;
关键词：
Salmonella; apoptosis; macrophages; epithelial cells; pathogen;
D O I：
10.1016/S1286-4579(01)01493-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A successful pathogen manipulates its host for its own benefit. One means to establish a successful infection, especially for intracellular pathogens, is to exploit host cell death pathways and alter the viability of host cells. Here we describe the manipulation of apoptosis by Salmonella and discuss the advantages that such actions may confer to the bacteria, and its implications in resistance to disease. (C) 2001 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码：1321 / 1326
页数：6
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