Coumaroyl flavonol glycosides from the leaves of Ginkgo biloba

被引:77
作者
Tang, YP
Lou, FC
Wang, JH
Li, YF
Zhuang, SF
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
[2] China Pharmaceut Univ, Dept Nat Med Chem, Nanjing 210038, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China
[4] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 200031, Peoples R China
关键词
Ginkgo bilobu L; ginkgoaceae; flavonol glycoside; antioxidant activity;
D O I
10.1016/S0031-9422(01)00320-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two coumaroyl flavonol glycosides, isorhamnetin 3-O-alpha -L-[6'''-p-coumaroyl-(beta -D)-glucopyranosyl-(1,2)-rhamnopyranoside], and kaempferol 3-O-alpha -L-[6'''-p-coumaroyl-(beta -D)-glucopyranosyl-(1,2)-rhamnopyranoside]-7-O-beta -D-glucopyranoside, were isolated from the n-BuOH extract of Ginkgo biloba leaves. These two, together with six other flavonol glycosides, kaempferol 3-O-alpha -L-[6'''-p-coumaroyl-(beta -D)-glucolpyranosyl-(1,2)-rhamnopyranoside], quercetin 3-O-alpha -L-[6'''-p-coumaroyl-(beta -D)-glucopyranosyl-(1,2)-rhamnopyranoside], quercetin 3-O-alpha -L-[6'''-p-coumaroyl-(beta -D)-glucopyranosyl-(1,2)-rhamnopyranoside]-7-O-beta -D-glucopyranoside, quercetin 3-O-beta -D-glucopyranosyl-(1-2)-alpha -L-rhamnopyranoside, quercetin 3-O-beta -rutinoside, and quercetin 3-O-beta -D-glucopyranoside, showed profound antioxidant activities in DPPH and cytochrome-c reduction assays using the HL-60 cell culture system. (C) 2001 Elsevier Science Lid, All rights reserved.
引用
收藏
页码:1251 / 1256
页数:6
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