Transcription factors for lens development assessed in vivo

被引:53
作者
Kondoh, H
机构
[1] Osaka Univ, Inst Mol & Cell Biol, Suita, Osaka 5650871, Japan
[2] Japan Sci & Technol Corp, Exploratory Res Adv Technol, Kondoh Differentiat Signaling Project, Sakyo Ku, Kyoto 6068305, Japan
关键词
D O I
10.1016/S0959-437X(99)80045-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Lens-cell differentiation occurs at a fairly early stage of embryogenesis and results in very simple tissue architecture. These features allow the embryonic lens to provide a paradigm of tissue development starting from tissue induction to tissue maturation. Not only have a number of transcription factors participating in lens development been identified but their actual functions are now assessed by modern approaches utilizing genetic and tissue manipulations of embryos.
引用
收藏
页码:301 / 308
页数:8
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