Transcription factors for lens development assessed in vivo

被引:53
作者
Kondoh, H
机构
[1] Osaka Univ, Inst Mol & Cell Biol, Suita, Osaka 5650871, Japan
[2] Japan Sci & Technol Corp, Exploratory Res Adv Technol, Kondoh Differentiat Signaling Project, Sakyo Ku, Kyoto 6068305, Japan
关键词
D O I
10.1016/S0959-437X(99)80045-8
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Lens-cell differentiation occurs at a fairly early stage of embryogenesis and results in very simple tissue architecture. These features allow the embryonic lens to provide a paradigm of tissue development starting from tissue induction to tissue maturation. Not only have a number of transcription factors participating in lens development been identified but their actual functions are now assessed by modern approaches utilizing genetic and tissue manipulations of embryos.
引用
收藏
页码:301 / 308
页数:8
相关论文
共 71 条
  • [51] HOMOLOGY OF THE EYELESS GENE OF DROSOPHILA TO THE SMALL EYE GENE IN MICE AND ANIRIDIA IN HUMANS
    QUIRING, R
    WALLDORF, U
    KLOTER, U
    GEHRING, WJ
    [J]. SCIENCE, 1994, 265 (5173) : 785 - 789
  • [52] PAX-6 IS ESSENTIAL FOR LENS-SPECIFIC EXPRESSION OF ZETA-CRYSTALLIN
    RICHARDSON, J
    CVEKL, A
    WISTOW, G
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (10) : 4676 - 4680
  • [53] Rat maf related genes: Specific expression in chondrocytes, lens and spinal cord
    Sakai, M
    Imaki, J
    Yoshida, K
    Ogata, A
    MatsushimaHibiya, Y
    Kuboki, Y
    Nishizawa, M
    Nishi, S
    [J]. ONCOGENE, 1997, 14 (06) : 745 - 750
  • [54] SANDILANDS A, 1995, J CELL SCI, V108, P1397
  • [55] Transcription factor AP-2 essential for cranial closure and craniofacial development
    Schorle, H
    Meier, P
    Buchert, M
    Jaenisch, R
    Mitchell, PJ
    [J]. NATURE, 1996, 381 (6579) : 235 - 238
  • [56] Lens-specific gene recruitment of ζ-crystallin through Pax6, Nrl-Maf, and brain suppressor sites
    Sharon-Friling, R
    Richardson, J
    Sperbeck, S
    Lee, D
    Rauchman, M
    Maas, R
    Swaroop, A
    Wistow, G
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (04) : 2067 - 2076
  • [57] Spemann H., 1901, VERHAND ANAT GES, V15, P61
  • [58] AN EVERTED REPEAT MEDIATES RETINOIC ACID INDUCTION OF THE GAMMA-F-CRYSTALLIN GENE - EVIDENCE OF A DIRECT ROLE FOR RETINOIDS IN LENS DEVELOPMENT
    TINI, M
    OTULAKOWSKI, G
    BREITMAN, ML
    TSUI, LC
    GIGUERE, V
    [J]. GENES & DEVELOPMENT, 1993, 7 (02) : 295 - 307
  • [59] Tomarev SI, 1996, DEV DYNAM, V206, P354, DOI 10.1002/(SICI)1097-0177(199608)206:4<354::AID-AJA2>3.0.CO
  • [60] 2-H