Characterization of Common Variable Immunodeficiency (CVID) Subgroups through Modulation of Their Interleukin-21 (aCD40/IL-4/IL-21) Pathway in Vitro

被引：0

作者：

Desjardins, Marylin ^{[1
]}

Beland, Marianne ^{[2
]}

Drolet, Jean-Philippe ^{[3
]}

Alizadehfar, Reza ^{[4
]}

Mazer, Bruce D. ^{[5
]}

机构：

[1] McGill Univ, Ctr Hlth, Dept Paediat, Div Allergy & Clin Immunol, Montreal, PQ, Canada

[2] MUHC, Montreal, PQ, Canada

[3] Ctr Hosp Univ Quebec, Quebec City, PQ, Canada

[4] McGill Univ, Ctr Hlth, Dept Paediat, Div Paediat Allergy & Clin Immunol, Montreal, PQ, Canada

[5] Montreal Childrens Hosp, Montreal, PQ H3H 1P3, Canada

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2015年 / 135卷 / 02期

关键词：

D O I：

10.1016/j.jaci.2014.12.1231

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

293

引用

页码：AB91 / AB91

页数：1

共 22 条

[1] Therapeutic Implications of the IL-21: IL-4 Receptor System in Children with Common Variable Immunodeficiency Syndrome
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KLINISCHE PADIATRIE, 2010, 222 (06): : 362 - 367
[2] Impaired in Vitro Capacity to Undergo IgG Isotype Class-Switching (ICS) in Response to Interleukin-21 (IL21) Stimulation in Common Variable Immunodeficiency (CVID)
Desjardins, Marylin
Mazer, Bruce D.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2013, 131 (02) : AB70 - AB70
[3] IL-2, IL-4 AND IFNγ production in common variable immunodeficiency (CVID).
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[4] Human IL-21 and IL-4 bind to partially overlapping epitopes of common γ-chain
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[5] Low phosphorylation of STAT-3 on interleukin-21 pathway in common variable immunodeficiency
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JOURNAL OF IMMUNOLOGY, 2012, 188
[6] Low Phosphorylation of STAT-3 on Interleukin-21 Pathway in Common Variable Immunodeficiency
Cesar Alcantara, Julio
Beron-Ruiz, Laura
Mogica-Martinez, Dolores
Elva Espinosa-Padilla, Sara
Javier Espinosa-Rosales, Francisco
Santos-Argumedo, Leopoldo
JOURNAL OF CLINICAL IMMUNOLOGY, 2012, 32 (02) : 390 - 391
[7] Modulation of the Interleukin-21 Pathway with Interleukin-4 Distinguishes Common Variable Immunodeficiency Patients with More Non-infectious Clinical Complications
Desjardins, Marylin
Beland, Marianne
Dembele, Marieme
Lejtenyi, Duncan
Drolet, Jean-Phillipe
Lemire, Martine
Tsoukas, Christos
Ben-Shoshan, Moshe
Noya, Francisco J. D.
Alizadehfar, Reza
McCusker, Christine T.
Mazer, Bruce D.
JOURNAL OF CLINICAL IMMUNOLOGY, 2018, 38 (01) : 45 - 55
[8] Modulation of the Interleukin-21 Pathway with Interleukin-4 Distinguishes Common Variable Immunodeficiency Patients with More Non-infectious Clinical Complications
Marylin Desjardins
Marianne Béland
Marieme Dembele
Duncan Lejtenyi
Jean-Phillipe Drolet
Martine Lemire
Christos Tsoukas
Moshe Ben-Shoshan
Francisco J. D. Noya
Reza Alizadehfar
Christine T. McCusker
Bruce D. Mazer
Journal of Clinical Immunology, 2018, 38 : 45 - 55
[9] CD40L-Stimulated B Lymphocytes Are Polarized toward APC Functions after Exposure to IL-4 and IL-21
Possamai, David
Page, Gabriel
Panes, Rebecca
Gagnon, Etienne
Lapointe, Rejean
JOURNAL OF IMMUNOLOGY, 2021, 207 (01): : 77 - 89
[10] Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency
Salzer, Elisabeth
Kansu, Aydan
Sic, Heiko
Majek, Peter
Ikinciogullari, Aydan
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Prengemann, Nina Kathrin
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Pickl, Winfried F.
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Ban, Sol A.
Kuloglu, Zarife
Demir, Arzu Meltem
Ensari, Arzu
Colinge, Jacques
Rizzi, Marta
Eibel, Hermann
Boztug, Kaan
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 133 (06) : 1651 - +

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