Nonrelevant Cerebral Atherosclerosis is a Strong Prognostic Factor in Acute Cerebral Infarction

被引：51

作者：

Kim, Jinkwon ^{[1
]}

Song, Tae-Jin ^{[2
]}

Song, Dongbeom ^{[2
]}

Lee, Hye Sun ^{[3
]}

Nam, Chung Mo ^{[3
]}

Nam, Hyo Suk ^{[2
]}

Kim, Young Dae ^{[2
]}

Heo, Ji Hoe ^{[2
]}

机构：

[1] CHA Univ, CHA Bundang Med Ctr, Songnam, South Korea

[2] Yonsei Univ, Coll Med, Dept Neurol, Seoul 120752, South Korea

[3] Yonsei Univ, Coll Med, Dept Biostat, Seoul 120752, South Korea

来源：

STROKE | 2013年 / 44卷 / 07期

关键词：

acute stroke; angiography; atherosclerosis; prognosis; STENOSIS; DISEASE;

D O I：

10.1161/STROKEAHA.113.001111

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose-We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke. Methods-We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI. Results-NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes. Conclusions-The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.

引用

页码：2013 / +

页数：10

共 7 条

[1] Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis [J].