Effect of Hydrophilic Monomer Distribution on Self-Assembly of a pH-Responsive Copolymer: Spheres, Worms and Vesicles from a Single Copolymer Composition

被引：44

作者：

Zhang, Junliang ^{[1
,2
,3
]}

Farias-Mancilla, Barbara ^{[4
]}

Kulai, Ihor ^{[4
]}

Hoeppener, Stephanie ^{[2
,3
]}

Lonetti, Barbara ^{[4
]}

Prevost, Sylvain ^{[5
]}

Ulbrich, Jens ^{[2
,3
]}

Destarac, Mathias ^{[4
]}

Colombani, Olivier ^{[6
]}

Schubert, Ulrich S. ^{[2
,3
]}

Guerrero-Sanchez, Carlos ^{[2
,3
]}

Harrisson, Simon ^{[7
]}

机构：

[1] Northwestern Polytech Univ, Sch Chem & Chem Engn, Shaanxi Key Lab Macromol Sci & Technol, Xian 710072, Shaanxi, Peoples R China

[2] Friedrich Schiller Univ Jena, Lab Organ & Macromol Chem IOMC, Humboldtstr 10 IOMC & Philosophenweg 7 JCSM, D-07743 Jena, Germany

[3] Friedrich Schiller Univ Jena, Jena Ctr Soft Matter JCSM, Humboldtstr 10 IOMC & Philosophenweg 7 JCSM, D-07743 Jena, Germany

[4] Univ Toulouse, IMRCP, UMR5623, 118 Route Narbonne, F-31062 Toulouse 9, France

[5] Inst Laue Langevin, 71 Ave Martyrs, Grenoble, France

[6] Le Mans Univ, Inst Mol & Materiaux Mans IMMM, CNRS, UMR 6283, Ave Olivier Messiaen, F-72085 Le Mans 9, France

[7] Univ Bordeaux, Ecole Natl Super Chim Biol & Phys, CNRS, LCPO,UMR 5629, 16 Ave Pey Berland, F-33607 Pessac, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2021年 / 60卷 / 09期

基金：

中国国家自然科学基金;

关键词：

copolymer; gradient copolymer; self-assembly; sequence control; stimuli-responsive; AMPHIPHILIC DIBLOCK COPOLYMERS; POLY(N-BUTYL ACRYLATE)-BLOCK-POLY(ACRYLIC ACID); SPONTANEOUS GRADIENT COPOLYMERS; MOLECULAR-WEIGHT DISTRIBUTION; BLOCK-COPOLYMERS; ACRYLIC-ACID; MICELLIZATION; MICELLES; SHAPE; TRANSITIONS;

D O I：

10.1002/anie.202010501

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of copolymers containing 50 mol % acrylic acid (AA) and 50 mol % butyl acrylate (BA) but with differing composition profiles ranging from an AA-BA diblock copolymer to a linear gradient poly(AA-grad-BA) copolymer were synthesized and their pH-responsive self-assembly behavior was investigated. While assemblies of the AA-BA diblock copolymer were kinetically frozen, the gradient-like compositions underwent reversible changes in size and morphology in response to changes in pH. In particular, a diblock copolymer consisting of two random copolymer segments of equal length (16 mol % and 84 mol % AA content, respectively) formed spherical micelles at pH >5, a mix of spherical and wormlike micelles at pH 5 and vesicles at pH 4. These assemblies were characterized by dynamic light scattering, cryo-transmission electron microscopy and small angle neutron scattering.

引用

页码：4925 / 4930

页数：6

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