Advances in the Study of the Structures and Bioactivities of Metabolites Isolated from Mangrove-Derived Fungi in the South China Sea

被引：26
作者：
Wang, Xin [1 ,2 ,3 ,4 ]
Mao, Zhi-Gang [1 ,2 ]
Song, Bing-Bing [3 ,4 ]
Chen, Chun-Hua [3 ,4 ]
Xiao, Wei-Wei [3 ,4 ]
Hu, Bin [1 ,2 ]
Wang, Ji-Wen [1 ,2 ]
Jiang, Xiao-Bing [1 ,2 ]
Zhu, Yong-Hong [3 ,4 ]
Wang, Hai-Jun [1 ,2 ]
机构：
[1] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurosurg, Guangzhou 510080, Guangdong, Peoples R China
[2] Sun Yat Sen Univ, Affiliated Hosp 1, Pituitary Tumour Ctr, Guangzhou 510080, Guangdong, Peoples R China
[3] Sun Yat Sen Univ, Sch Med, Dept Histol & Embryol, Guangzhou 510080, Guangdong, Peoples R China
[4] Sun Yat Sen Univ, Dept Educ Guangdong Prov, Key Lab Funct Mol Marine Microorganisms, Guangzhou 510080, Guangdong, Peoples R China
来源：
MARINE DRUGS | 2013年 / 11卷 / 10期
基金：
中国国家自然科学基金;
关键词：
marine metabolites; fungus; mangrove; biological activity; south China sea; SECALONIC ACID D; MARINE NATURAL-PRODUCTS; XYLOKETAL B PROTECTS; STRUCTURE ELUCIDATION; NMR ASSIGNMENTS; XANTHONE DERIVATIVES; ANTICANCER ACTIVITY; CELLS; APOPTOSIS; COMPOUND;
D O I：
10.3390/md11103601
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Many metabolites with novel structures and biological activities have been isolated from the mangrove fungi in the South China Sea, such as anthracenediones, xyloketals, sesquiterpenoids, chromones, lactones, coumarins and isocoumarin derivatives, xanthones, and peroxides. Some compounds have anticancer, antibacterial, antifungal and antiviral properties, but the biosynthesis of these compounds is still limited. This review summarizes the advances in the study of secondary metabolites from the mangrove-derived fungi in the South China Sea, and their biological activities reported between 2008 and mid-2013.
引用
收藏
页码：3601 / 3616
页数：16
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