High-Frequency Ventilation as a Mode of Noninvasive Respiratory Support

被引：24

作者：

Mukerji, Amit ^{[1
]}

Dunn, Michael ^{[2
,3
]}

机构：

[1] McMaster Univ, McMaster Childrens Hosp, Dept Pediat, Div Neonatol, 1280 Main St West,HSC-4F1E, Hamilton, ON L8S 4K1, Canada

[2] Univ Toronto, Dept Pediat, Toronto, ON, Canada

[3] Sunnybrook Hlth Sci Ctr, Dept Newborn & Dev Pediat, Room M4-222,2075 Bayview Ave, Toronto, ON M4N 3M5, Canada

来源：

CLINICS IN PERINATOLOGY | 2016年 / 43卷 / 04期

关键词：

Noninvasive high-frequency ventilation; Ventilator-induced lung injury; Bronchopulmonary dysplasia; Nasal intermittent positive pressure ventilation; Ventilation efficacy; Postextubation prophylaxis; Alveolar development; POSITIVE AIRWAY PRESSURE; BIRTH-WEIGHT INFANTS; INDUCED LUNG INJURY; OSCILLATORY VENTILATION; MECHANICAL VENTILATION; PRETERM INFANTS; NASAL VENTILATION; PREMATURE-INFANTS; CARBON-DIOXIDE; CPAP;

D O I：

10.1016/j.clp.2016.07.008

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

High-frequency ventilation (HFV) as a mode of noninvasive respiratory support (NRS) in preterm neonates is gaining popularity. Benefits may accrue from combining the ventilatory efficiency of HFV delivered through a noninvasive interface, enhancing respiratory support while potentially limiting lung injury. Current evidence suggests that noninvasive HFV (NIHFV) may be superior to other NRS modes in eliminating carbon dioxide and preventing endotracheal ventilation after failure of other NRS modes. Animal data suggest NIHFV may promote improved alveolar development compared to endotracheal ventilation. However, adequately powered large-scale controlled trials are required to evaluate efficacy and safety prior to widespread use of NIHFV.

引用

页码：725 / +

页数：17

共 63 条

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