National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

被引:21
作者
Liu, Po-Yu [1 ]
Lee, Yu-Lin [2 ]
Lu, Min-Chi [3 ]
Shao, Pei-Lan [4 ]
Lu, Po-Liang [5 ]
Chen, Yen-Hsu [5 ]
Cheng, Shu-Hsing [6 ,7 ]
Ko, Wen-Chien [8 ]
Lin, Chi-Ying [9 ]
Wu, Ting-Shu [10 ]
Yen, Muh-Yong [11 ,12 ]
Wang, Lih-Shinn [13 ,14 ]
Liu, Chang-Pan [15 ,16 ]
Lee, Wen-Sen [17 ,18 ]
Chen, Yao-Shen [12 ,19 ]
Wang, Fu-Der [12 ,20 ]
Tseng, Shu-Hui [21 ]
Lin, Chao-Nan [22 ,23 ]
Tang, Hung-Jen [24 ]
Chen, Yu-Hui [25 ,26 ]
Sheng, Wang-Huei [27 ]
Lee, Chun-Ming [28 ,29 ]
Liao, Ming-Huei [30 ]
Hsueh, Po-Ren [27 ,31 ]
机构
[1] Taichung Vet Gen Hosp, Dept Internal Med, Taichung, Taiwan
[2] Changhua Christian Hosp, Dept Internal Med, Changhua, Taiwan
[3] China Med Univ, Sch Med, Dept Microbiol & Immunol, Taichung, Taiwan
[4] Natl Taiwan Univ Hosp, Hsin Chu Branch, Dept Pediat, Hsinchu, Taiwan
[5] Kaohsiung Med Univ, Kaohsiung Med Univ Hosp, Coll Med, Dept Internal Med, Kaohsiung, Taiwan
[6] Taoyuan Gen Hosp, Dept Internal Med, Minist Hlth Welf, Taoyuan, Taiwan
[7] Taipei Med Univ, Coll Publ Hlth & Nutr, Sch Publ Hlth, Taipei, Taiwan
[8] Natl Cheng Kung Univ, Dept Internal Med, Med Coll & Hosp, Tainan, Taiwan
[9] Natl Taiwan Univ Hosp, Dept Internal Med, Yun Lin Branch, Yunlin, Taiwan
[10] Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Internal Med, Div Infect Dis,Coll Med, Taoyuan, Taiwan
[11] Taipei City Hosp, Div Infect Dis, Taipei, Taiwan
[12] Natl Yang Ming Univ, Sch Med, Taipei, Taiwan
[13] Buddhist Tzu Chi Gen Hosp, Dept Internal Med, Div Infect Dis, Hualien, Taiwan
[14] Tzu Chi Univ, Hualien, Taiwan
[15] MacKay Mem Hosp, Dept Internal Med, Div Infect Dis, Taipei, Taiwan
[16] MacKay Med Coll, New Taipei, Taiwan
[17] Taipei Med Univ, Wan Fang Hosp, Dept Internal Med, Div Infect Dis, Taipei, Taiwan
[18] Taipei Med Univ, Sch Med, Coll Med, Dept Internal Med, Taipei, Taiwan
[19] Kaohsiung Vet Gen Hosp, Dept Internal Med, Kaohsiung, Taiwan
[20] Taipei Vet Gen Hosp, Dept Med, Div Infect Dis, Taipei, Taiwan
[21] Minist Hlth & Welf, Ctr Dis Control & Prevent, Taipei, Taiwan
[22] Natl Pingtung Univ Sci & Technol, Coll Vet Med, Dept Vet Med, Pingtung, Taiwan
[23] Natl Pingtung Univ Sci & Technol, Coll Vet Med, Anim Dis Diagnost Ctr, Pingtung, Taiwan
[24] Chi Mei Med Ctr, Dept Med, Tainan, Taiwan
[25] Kaohsiung Med Univ Hosp, Dept Internal Med, Div Infect Dis, Kaohsiung, Taiwan
[26] Kaohsiung Med Univ, Grad Inst Med, Coll Med, Sch Med,Sepsis Res Ctr, Kaohsiung, Taiwan
[27] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Internal Med, Div Infect Dis,Coll Med, Taipei, Taiwan
[28] St Josephs Hosp, Dept Internal Med, Huwei Township, Yunlin, Taiwan
[29] MacKay Jr Coll Med Nursing & Management, Taipei, Taiwan
[30] Natl Pingtung Univ Sci & Technol, Neipu, Taiwan
[31] Natl Taiwan Univ, Natl Taiwan Univ Hosp, Dept Lab Med, Coll Med, Taipei, Taiwan
关键词
Enterobacteriaceae; KPC; carbapenemases; colistin; mcr-1; INTENSIVE-CARE UNITS; ESCHERICHIA-COLI; KLEBSIELLA-PNEUMONIAE; INFECTIONS; CARBAPENEMS; SPREAD; AGENTS; RATES;
D O I
10.1128/AAC.01089-20
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A multicenter collection of bacteremic isolates of Escherichia coli (n = 423), Klebsiella pneumoniae (n = 372), Pseudomonas aeruginosa (n = 300), and Acinetobacter baumannii complex (n = 199) was analyzed for susceptibility. Xpert Carba-R assay and sequencing for mcr genes were performed for carbapenem- or colistin-resistant isolates. Nineteen (67.8%) carbapenem-resistant K. pneumoniae (n = 28) and one (20%) carbapenem-resistant E. coli (n = 5) isolate harbored bla(KPC) (n = 17), bla(OXA-48) (n = 2), and bla(VIM) (n = 1) genes.
引用
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页数:8
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