Direct Electrochemical Carboxylation of Benzylic C-N Bonds with Carbon Dioxide

被引：121

作者：

Yang, Deng-Tao ^{[1
]}

Zhu, Minghui ^{[1
]}

Schiffer, Zachary J. ^{[1
]}

Williams, Kindle ^{[1
]}

Song, Xiaojie ^{[2
]}

Liu, Xiaohui ^{[2
]}

Manthiram, Karthish ^{[1
]}

机构：

[1] MIT, Dept Chem Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA

[2] East China Univ Sci & Technol, Res Inst Ind Catalysis, Shanghai 200237, Peoples R China

来源：

ACS CATALYSIS | 2019年 / 9卷 / 05期

关键词：

electrochemistry; carboxylation; carbon dioxide; carboxylic acids; C-N bond;

D O I：

10.1021/acscatal.9b00818

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We report a direct and efficient electrochemical carboxylation of benzylic C-N bonds with CO2 at room temperature. The reaction has been successfully applied to both primary and secondary benzylic C-N bonds with the compatibility of a variety of functional groups. This procedure does not require stoichiometric metals, external reducing agents, or sacrificial anodes, making column chromatography unnecessary for product purification. Differential electrochemical mass spectrometry (DEMS) was used to elucidate key intermediates of the electrocarboxylation reaction.

引用

页码：4699 / 4705

页数：13

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