Unifying homology effects

被引：7

作者：

Cogoni, C ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Biotecnol Cellulari & Ematol, I-00161 Rome, Italy

来源：

NATURE GENETICS | 2002年 / 30卷 / 03期

关键词：

D O I：

10.1038/ng0302-245

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Meiotic silencing by unpaired DNA is a new mechanism, related to other homology-dependent gene silencing phenomena, with implications not only for genome protection against invasive nucleic acids but for genome maintenance and speciation as well.

引用

页码：245 / 246

页数：2

共 13 条

[1] Meiotic transvection in fungi [J].

Aramayo, R ;

Metzenberg, RL .

CELL, 1996, 86 (01) :103-113

[2]

BENSTEIN E, 2001, NATURE, V409, P363

[3] Cosuppression comes to the animals [J].

Bingham, PM .

CELL, 1997, 90 (03) :385-387

[4] Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase [J].

Cogoni, C ;

Macino, G .

NATURE, 1999, 399 (6732) :166-169

[5] Post-transcriptional gene silencing across kingdoms [J].

Cogoni, C ;

Macino, G .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 2000, 10 (06) :638-643

[6] An RNA-Dependent RNA polymerase gene in Arabidopsis is required for posttranscriptional gene silencing mediated by a transgene but not by a virus [J].

Dalmay, T ;

Hamilton, A ;

Rudd, S ;

Angell, S ;

Baulcombe, DC .

CELL, 2000, 101 (05) :543-553

[7] RNA interference is mediated by 21-and 22-nucleotide RNAs [J].

Elbashir, SM ;

Lendeckel, W ;

Tuschl, T .

GENES & DEVELOPMENT, 2001, 15 (02) :188-200

[8] Argonaute2, a link between genetic and biochemical analyses of RNAi [J].

Hammond, SM ;

Boettcher, S ;

Caudy, AA ;

Kobayashi, R ;

Hannon, GJ .

SCIENCE, 2001, 293 (5532) :1146-1150

[9] Arabidopsis SGS2 and SGS3 genes are required for posttranscriptional gene silencing and natural virus resistance [J].

Mourrain, P ;

Béclin, C ;

Elmayan, T ;

Feuerbach, F ;

Godon, C ;

Morel, JB ;

Jouette, D ;

Lacombe, AM ;

Nikic, S ;

Picault, N ;

Rémoué, K ;

Sanial, M ;

Vo, TA ;

Vaucheret, H .

CELL, 2000, 101 (05) :533-542

[10] Meiotic silencing by unpaired DNA [J].

Shiu, PKT ;

Raju, NB ;

Zickler, D ;

Metzenberg, RL .

CELL, 2001, 107 (07) :905-916

← 1 2 →