An efficient one-pot three-component synthesis of pyrimido[4,5-d]pyrimidine derivatives in aqueous medium

被引：15

作者：

Badvel, Sreedhar ^{[1
]}

Gopireddy, Raveendra Reddy ^{[1
]}

Shaik, Thaslim Basha ^{[2
]}

Hasti, Sudhamani ^{[2
]}

Tummaluru, Veera Reddy ^{[1
]}

Chamarthi, Naga Raju ^{[2
]}

机构：

[1] Vikrama Simhapuri Univ, Dept Chem, Nellore 524003, Andhra Pradesh, India

[2] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2015年 / 51卷 / 08期

关键词：

6-amino-N; N-dimethyluracil; phenylisocyanate; phenylisothiocyanate; Lewis acid; PEG-bound sulfonic acid; three-component reaction; POLYMERIC CATALYST; PEG-SO3H; MICROWAVE; WATER; 3,4-DIHYDROPYRIMIDONES; EPOXIDES; URACILS; SOLVENT; ROUTE;

D O I：

10.1007/s10593-015-1769-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A fast, efficient, and green synthesis of pyrimido[4,5-d]pyrimidine derivatives has been achieved via one-pot three-component reaction starting from 6-amino-N,N-dimethyluracil, phenylisothiocyanate or phenylisocyanate, and aromatic aldehydes in the presence of polyethylene glycol-bound sulfonic acid as a catalyst in water as solvent.

引用

页码：749 / 753

页数：5

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