Historical Overview of Transplantation

被引:113
作者
Barker, Clyde F. [1 ,2 ,3 ]
Markmann, James F. [2 ,3 ]
机构
[1] Hosp Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
[2] Harvard Univ, Sch Med, Dept Surg, Boston, MA 02114 USA
[3] Massachusetts Gen Hosp, Div Transplantat, Boston, MA 02114 USA
关键词
DONOR BONE-MARROW; SKIN HOMOGRAFTS; HUMAN-KIDNEY; RENAL HOMOTRANSPLANTATION; IMMUNOLOGICAL-TOLERANCE; CYCLOSPORIN-A; CLINICAL TRANSPLANTATION; ANTILYMPHOCYTIC-SERUM; IDENTICAL-TWINS; THORACIC-DUCT;
D O I
10.1101/cshperspect.a014977
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Except for legends and claims of miracles, most histories of transplantation cover only the last 60 years because there were no earlier successes. However, the story of even this era has been documented in such rich detail that a full account would fill several volumes. Thus, this brief summary must be limited to highly selected "landmarks." Some landmarks had an immediate impact, but the importance of others went unrecognized for decades. Some findings that deserved landmark status were overlooked or forgotten, whereas others of no biological significance had major impact. Placing these events in perspective is challenging. Several of transplantation's pioneers are still alive, and most of the others are within living memory. Virtually all of them have produced their own accounts. For the most part, they agree on what the "landmarks" are, but their differences in emphasis and perspective make an interesting story.
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页数:18
相关论文
共 119 条
[1]   THE USE OF SKIN GRAFTING TO DISTINGUISH BETWEEN MONOZYGOTIC AND DIZYGOTIC TWINS IN CATTLE [J].
ANDERSON, D ;
BILLINGHAM, RE ;
LAMPKIN, GH ;
MEDAWAR, PB .
HEREDITY, 1951, 5 (03) :379-+
[2]  
[Anonymous], 1931, Science, V73, P566
[3]   LONG-TERM RESULTS OF A CONTROLLED PROSPECTIVE-STUDY WITH TRANSFUSION OF DONOR-SPECIFIC BONE-MARROW IN 57 CADAVERIC RENAL-ALLOGRAFT RECIPIENTS [J].
BARBER, WH ;
MANKIN, JA ;
LASKOW, DA ;
DEIERHOI, MH ;
JULIAN, BA ;
CURTIS, JJ ;
DIETHELM, AG .
TRANSPLANTATION, 1991, 51 (01) :70-75
[4]   THE USE OF UW-SOLUTION IN CLINICAL TRANSPLANTATION - A 4-YEAR EXPERIENCE [J].
BELZER, FO ;
DALESSANDRO, AM ;
HOFFMANN, RM ;
KNECHTLE, SJ ;
REED, A ;
PIRSCH, JD ;
KALAYOGLU, M ;
SOLLINGER, HW ;
BUSUTTIL, RW ;
DIETHELM, G .
ANNALS OF SURGERY, 1992, 215 (06) :579-585
[5]  
BELZER FO, 1967, LANCET, V2, P536
[6]   ACTIVELY ACQUIRED TOLERANCE OF FOREIGN CELLS [J].
BILLINGHAM, RE ;
BRENT, L ;
MEDAWAR, PB .
NATURE, 1953, 172 (4379) :603-606
[7]   EFFECT OF CORTISONE ON SURVIVAL OF SKIN HOMOGRAFTS IN RABBITS [J].
BILLINGHAM, RE ;
KROHN, PL ;
MEDAWAR, PB .
BMJ-BRITISH MEDICAL JOURNAL, 1951, 1 (4716) :1158-1163
[8]   PIGMENT SPREAD AND CELL HEREDITY IN GUINEA-PIGS SKIN [J].
BILLINGHAM, RE ;
MEDAWAR, PB .
HEREDITY, 1948, 2 (01) :29-&
[9]  
Billingham RE, 1991, HIST TRANSPLANTATION, P73
[10]   BIOLOGICAL EFFECTS OF CYCLOSPORIN-A - NEW ANTILYMPHOCYTIC AGENT [J].
BOREL, JF ;
FEURER, C ;
GUBLER, HU ;
STAHELIN, H .
AGENTS AND ACTIONS, 1976, 6 (04) :468-475