Spectrophotometric determination of prochlorperazine maleate in pure and pharmaceutical preparations

被引：4

作者：

Aman, T ^{[1
]}

Majeed, Z ^{[1
]}

Kazi, AA ^{[1
]}

Khan, IU ^{[1
]}

机构：

[1] Govt Coll, Dept Chem, Lahore 54000, Pakistan

来源：

MIKROCHIMICA ACTA | 2002年 / 138卷 / 1-2期

关键词：

prochlorperazine maleate; spectrophotometry; pharmaceutical analysis;

D O I：

10.1007/s006040200001

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Prochlorperazine maleate reacts with l-naphthylamine and sodium nitrite, after heating for 110s at 80degreesC to give an orange red colour having maximum absorbance at 460 nm. The reaction is selective for prochlorperazine maleate with 0.01 mg/mL as visual limit of quantitation and provides a basis for a new spectrophotometric determination. The colour reaction obeys Beer's law from 0.01mg/10mL to 0.33mg/10mL of prochlorperazine maleate and the relative standard deviation is 0.68%. The quantitative assessment of tolerable amounts of other drugs is also studied.

引用

页码：13 / 17

页数：5

共 30 条

[1]

Aman T, 1997, ANAL LETT, V30, P1517, DOI 10.1080/00032719708001672

[2] SPECTROPHOTOMETRIC DETERMINATION OF STREPTOMYCIN [J].