The clinical significance of an autoimmune response against glutamic acid decarboxylase

被引：96
作者：
Ellis, TM
Atkinson, MA
机构：
来源：
NATURE MEDICINE | 1996年 / 2卷 / 02期
关键词：
D O I：
10.1038/nm0296-148
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Glutamic acid decarboxylase is attracting much interest because of its putative involvement in two clinical disorders: stiff-man syndrome and insulin-dependent diabetes. Here we discuss the clinical significance of an autoimmune response against GAD and consider how such information may help identify the disease mechanisms of these disorders.
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页码：148 / 153
页数：6
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