Recommendations for the use of long-term central venous catheter (CVC) in children with hemato-oncological disorders: management of CVC-related occlusion and CVC-related thrombosis. On behalf of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP)

被引：42

作者：

Giordano, Paola ^{[1
]}

Saracco, Paola ^{[2
]}

Grassi, Massimo ^{[1
]}

Luciani, Matteo ^{[3
]}

Banov, Laura ^{[4
]}

Carraro, Francesca ^{[5
]}

Crocoli, Alessandro ^{[6
]}

Cesaro, Simone ^{[7
]}

Zanazzo, Giulio Andrea ^{[8
]}

Molinari, Angelo Claudio ^{[4
]}

机构：

[1] Univ Bari Aldo Moro, Dept Biomed & Human Oncol, Pediat Unit, Bari, Italy

[2] Univ Turin, Dept Pediat, Hematol Unit, I-10124 Turin, Italy

[3] Bambino Gesu Children Hosp, Dept Pediat Hematol Oncol, Rome, Italy

[4] Giannina Gaslini Childrens Hosp, Thrombosis & Hemostasis Unit, Genoa, Italy

[5] Osped Infantile Regina Margherita, Pediat Hematol Oncol & Bone Marrow Unit, Turin, Italy

[6] Bambino Gesu Children Hosp, Dept Surg, Gen & Thorac Surg Unit, Rome, Italy

[7] Univ Integrata, Azienda Osped, Pediat Hematol Oncol Unit, Verona, Italy

[8] Inst Maternal & Child Hlth IRCCS Burlo Garofolo, Trieste, Italy

来源：

ANNALS OF HEMATOLOGY | 2015年 / 94卷 / 11期

关键词：

Central venous catheter; Thrombosis; Pediatric hematology oncology; CVC occlusion; ACUTE LYMPHOBLASTIC-LEUKEMIA; DEEP-VEIN THROMBOSIS; TISSUE-PLASMINOGEN ACTIVATOR; SODIUM-HYDROXIDE SOLUTION; MOLECULAR-WEIGHT HEPARIN; LINE-RELATED THROMBOSIS; HYDROCHLORIC-ACID; RISK-FACTORS; VASCULAR ACCESS; POSTTHROMBOTIC SYNDROME;

D O I：

10.1007/s00277-015-2481-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Central venous catheters (CVC), used for the management of children with hemato-oncological disorders, are burdened by a significant incidence of mechanical, infective, or thrombotic complications. These complications favor an increasing risk in prolongation of hospitalization, extra costs of care, and sometimes severe life-threatening events. No guidelines for the management of CVC-related occlusion and CVC-related thrombosis are available for children. To this aim, members of the coagulation defects working group and the supportive therapy working group of the Italian Association of Pediatric Hematology and Oncology (AIEOP) reviewed the pediatric and adult literature to propose the first recommendations for the management of CVC-related occlusion and CVC-related thrombosis in children with hemato-oncological disorders.

引用

页码：1765 / 1776

页数：12

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