1,6-Addition of Tertiary Carbon Radicals Generated From Alcohols or Carboxylic Acids by Visible-Light Photoredox Catalysis

被引：45
作者：
Abbas, Samir Y. [1 ,2 ]
Zhao, Peng [1 ]
Overman, Larry E. [1 ]
机构：
[1] Univ Calif Irvine, Dept Chem, Irvine, CA 92697 USA
[2] Natl Res Ctr, Organometall & Organometalloid Chem Dept, Cairo 12622, Egypt
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 03期
关键词：
STEREOGENIC CENTERS; ACTIVATED ALKENES; 1,3-DIENES;
D O I：
10.1021/acs.orglett.7b04034
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The addition of tertiary carbon radicals generated by an Ir-catalyzed visible-light photocatalyst to electron-deficient 1,3-dienes proceeds in good yields to append a delta-substituted beta,gamma-unsaturated carbonyl fragment to a tertiary alcohol or carboxylic acid precursor and construct a new quaternary carbon center.
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收藏
页码：868 / 871
页数：4
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