Transmission dynamic and backward bifurcation of Middle Eastern respiratory syndrome coronavirus

被引:0
作者
Fatima, Bibi [1 ]
Zaman, Gul [2 ]
Jarad, Fahd [3 ]
机构
[1] Univ Malakand Chakdara, Dir Lower, Khyber Pakhtunkhwa, Pakistan
[2] Cankaya Univ, Dept Math, Ankara, Turkey
[3] China Med Univ, China Med Univ Hosp, Dept Med Res, Taichung, Taiwan
来源
NONLINEAR ANALYSIS-MODELLING AND CONTROL | 2022年 / 27卷 / 01期
关键词
epidemic model; reproductive number; stability analysis; backward bifurcation; numerical simulation; EPIDEMIC; DISEASE;
D O I
10.15388/namc.2022.27.25256
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
Middle East respiratory syndrome coronavirus (MERS-CoV) remains an emerging disease threat with regular human cases on the Arabian Peninsula driven by recurring camels to human transmission events. In this paper, we present a new deterministic model for the transmission dynamics of (MERS-CoV). In order to do this, we develop a model formulation and analyze the stability of the proposed model. The stability conditions are obtained in term of R-0, we find those conditions for which the model become stable. We discuss basic reproductive number R-0 along with sensitivity analysis to show the impact of every epidemic parameter. We show that the proposed model exhibits the phenomena of backward bifurcation. Finally, we show the numerical simulation of our proposed model for supporting our analytical work. The aim of this work is to show via mathematical model the transmission of MERS-CoV between humans and camels, which are suspected to be the primary source of infection.
引用
收藏
页码:54 / 69
页数:16
相关论文
共 19 条
[1]   Middle East Respiratory Syndrome Coronavirus: A Case-Control Study of Hospitalized Patients [J].
Al-Tawfiq, Jaffar A. ;
Hinedi, Kareem ;
Ghandour, Jihad ;
Khairalla, Hanan ;
Musleh, Samir ;
Ujayli, Alaa ;
Memish, Ziad A. .
CLINICAL INFECTIOUS DISEASES, 2014, 59 (02) :160-165
[2]  
Alagaili AN, 2014, MBIO, V5, DOI [10.1128/mBio.00884-14, 10.1128/mBio.01482-14]
[3]   Clinical Course and Outcomes of Critically Ill Patients With Middle East Respiratory Syndrome Coronavirus Infection [J].
Arabi, Yaseen M. ;
Arifi, Ahmed A. ;
Balkhy, Hanan H. ;
Najm, Hani ;
Aldawood, Abdulaziz S. ;
Ghabashi, Alaa ;
Hawa, Hassan ;
Alothman, Adel ;
Khaldi, Abdulaziz ;
Al Raiy, Basel .
ANNALS OF INTERNAL MEDICINE, 2014, 160 (06) :389-+
[4]   Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study [J].
Assiri, Abdullah ;
Al-Tawfiq, Jaffar A. ;
Al-Rabeeah, Abdullah A. ;
Al-Rabiah, Fahad A. ;
Al-Hajjar, Sami ;
Al-Barrak, Ali ;
Flemban, Hesham ;
Al-Nassir, Wafa N. ;
Balkhy, Hanan H. ;
Al-Hakeem, Rafat F. ;
Makhdoom, Hatem Q. ;
Zumla, Alimuddin I. ;
Memish, Ziad A. .
LANCET INFECTIOUS DISEASES, 2013, 13 (09) :752-761
[5]   Evidence for Camel-to-Human Transmission of MERS Coronavirus [J].
Azhar, Esam I. ;
El-Kafrawy, Sherif A. ;
Farraj, Suha A. ;
Hassan, Ahmed M. ;
Al-Saeed, Muneera S. ;
Hashem, Anwar M. ;
Madani, Tariq A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (26) :2499-2505
[6]   The epidemiology of MERS-CoV [J].
Fisman, David N. ;
Tuite, Ashleigh R. .
LANCET INFECTIOUS DISEASES, 2014, 14 (01) :6-7
[7]   Contribution to the mathematical theory of epidemics [J].
Kermack, WO ;
McKendrick, AG .
PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES A-CONTAINING PAPERS OF A MATHEMATICAL AND PHYSICAL CHARACTER, 1927, 115 (772) :700-721
[8]   Modeling and control of the hepatitis B virus spreading using an epidemic model [J].
Khan, Tahir ;
Ullah, Zakir ;
Ali, Zakir ;
Zaman, Gul .
CHAOS SOLITONS & FRACTALS, 2019, 124 :1-9
[9]   The transmission dynamic and optimal control of acute and chronic hepatitis B [J].
Khan, Tahir ;
Zaman, Gul ;
Chohan, M. Ikhlaq .
JOURNAL OF BIOLOGICAL DYNAMICS, 2017, 11 (01) :172-189
[10]  
Kim Yunhwan, 2016, Osong Public Health Res Perspect, V7, P49, DOI 10.1016/j.phrp.2016.01.001