Progressive Parkinsonism Three Years after Shunt Surgery in a Patient with Idiopathic Normal Pressure Hydrocephalus

被引：4

作者：

Shimada, Hitoshi ^{[1
,2
]}

Shimada, Yasuo ^{[2
]}

机构：

[1] Natl Inst Quantum & Radiol Sci & Technol QST, Natl Inst Radiol Sci NIRS, Dept Funct Brain Imaging Res DOFI, Chiba, Japan

[2] Shimada Hosp, Ogori, Fukuoka, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 17期

关键词：

idiopathic normal pressure hydrocephalus; All Clinical Neurology; Parkinson's disease/Parkinsonism; I-123-MIBG myocardial scintigraphy; dopamine transporter imaging; DIAGNOSTIC-CRITERIA; MANAGEMENT;

D O I：

10.2169/internalmedicine.4553-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An 86-year-old man, who had undergone a lumboperitoneal shunt for idiopathic normal pressure hydrocephalus (iNPH) implanted 4 years earlier showed progressive parkinsonism for the past year. His clinical symptoms, including resting tremor and rapid eye movement sleep behavior disorder, responsiveness to levodopa, and abnormal findings on I-123-meta-iodobenzylguanidine myocardial scintigraphy and dopamine transporter imaging, indicated that his pathological background of parkinsonism included concomitant synucleinopathy, such as Parkinson's disease or dementia with Lewy bodies, in addition to iNPH. Clinicians should consider the possibility of concomitant proteinopathies and their treatments when clinical symptoms become evident after shunt operations in patients with iNPH.

引用

页码：2183 / 2186

页数：4

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