Vaccine-related autoimmune hepatitis: the same disease as idiopathic autoimmune hepatitis? Two clinical reports and review

被引:30
作者
van Gemeren, Marline A. J. [1 ]
van Wijngaarden, Peter [1 ]
Doukas, Michael [2 ]
de Man, Robert A. [3 ]
机构
[1] Amphia Ziekenhuis Locatie Molengracht, Dept Internal Med & Gastroenterol, Breda, Netherlands
[2] Erasmus Univ, Med Ctr Rotterdam, Dept Pathol, Rotterdam, Netherlands
[3] Erasmus Univ, Med Ctr, Dept Gastroenterol & Hepatol, Rotterdam, Netherlands
关键词
Hepatitis A virus; autoimmune hepatitis; vaccination; autoimmunity; A VIRUS-INFECTION; ADJUVANTS;
D O I
10.1080/00365521.2016.1224379
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Autoimmune hepatitis (AIH) develops in genetically predisposed individuals after an inciting or environmental trigger. These factors are unknown but may include viral infections, environmental toxins, drugs and vaccinations. Few reports are written about vaccination as potential trigger of autoimmune hepatitis. In this article, we additionally describe two vaccine-related cases of AIH. In both cases, long-term immune-suppressive therapy is demanded. Moreover, we present the cases of vaccine-related AIH from literature and compare these with idiopathic AIH and our own cases.
引用
收藏
页码:18 / 22
页数:5
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