The Intriguing Role of Histamine in Exercise Responses

被引：20

作者：

Luttrell, Meredith J. ^{[1
]}

Halliwill, John R. ^{[1
]}

机构：

[1] Univ Oregon, Dept Human Physiol, Eugene, OR 97403 USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2017年 / 45卷 / 01期

基金：

美国国家卫生研究院;

关键词：

endurance exercise; gene expression; histamine; antihistamines; receptors; molecular transducers of physical activity; recovery from exercise; SUSTAINED POSTEXERCISE VASODILATATION; HISTIDINE-DECARBOXYLASE; MECHANICAL HYPERALGESIA; RECEPTOR ACTIVATION; SKELETAL-MUSCLE; MAST-CELL; ANTIHISTAMINE; INGESTION; FATIGUE; STRESS;

D O I：

10.1249/JES.0000000000000093

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

In humans, histamine is a molecular transducer of physical activity responses, and antihistamines modify more than 25% of the genes responding to exercise. Although the upstream signal that results in release of histamine within exercising skeletal muscle remains to be identified, it is likely a fundamental exercise response and not an allergic reaction.

引用

页码：16 / 23

页数：8

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