Nickel-Catalyzed Alkenylation and Alkylation of Fluoroarenes via Activation of C-H Bond over C-F Bond

被引：251

作者：

Nakao, Yoshiaki ^{[1
]}

Kashihara, Natsuko ^{[1
]}

Kanyiva, Kyalo Stephen ^{[1
]}

Hiyama, Tamejiro ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Kyoto 6158510, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2008年 / 130卷 / 48期

关键词：

D O I：

10.1021/ja807258m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nickel/P(c-C(5)H(9))(3) (PCyp(3)) catalyst effects the addition reactions of fluoroarenes across alkynes, 1,3-dienes, and vinylarenes via the activation of C-H bonds over C-F bonds. The acidic C-H bonds located ortho to fluorine are exclusively activated to afford a range of alkenylated and alkylated fluoroarenes.

引用

页码：16170 / +

页数：3

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