Non-dipping morning blood pressure and isolated systolic hypertension in elderly

被引:6
作者
Zain-El Abdin, M. H. [1 ]
Snincak, M. [1 ]
Pahuli, K. [1 ]
Solarova, Z. [1 ]
Hrabcakova, P. [1 ]
机构
[1] PJ Safarikiensis Univ, Sch Med, Clin Geriatr & Hlth Care, Ctr Res Diag & Treatment Hypertens, SK-04001 Kosice, Slovakia
来源
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY | 2013年 / 114卷 / 03期
关键词
isolated systolic hypertension; early morning blood pressure surge; dippers; nondippers; PROGNOSTIC-SIGNIFICANCE; PHYSICAL-ACTIVITY; HEART-RATE; SURGE; MORBIDITY; EVENTS; OFFICE; STROKE; SILENT; RISK;
D O I
10.4149/BLL_2013_033
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Morning hypertension is currently the blind spot in the clinical practice of hypertension, home 24-hour blood pressure measurement has been recommended in patients with a high clinic blood pressure and patients with target organ damage. Aim: To assess whether an increased early morning blood pressure surge, established via a single 24-hour blood pressure monitoring, in treated elderly hypertensive's is related to more prominent target organ damage. Material and methods: 310 treated hypertensive patients randomly attended the out-patient clinic of our hypertension centre. The patients were divided in 2 groups: systolic/diastolic blood pressure hypertension (n = 266) and isolated systolic hypertension (n = 44 76 +/- 10 yrs). Results: Equivalent in both males and females, despite the rise in nondippers with an early morning surge (higher in females). Hyperlipidemia arises equally in dippers and nondippers, 45 % of nondippers had diabetes mellitus; 30 % suffered previous renal insufficiency and about 29 % of patients suffered from an endocrine disorder, mostly thyroid. Metabolic syndrome was only found to be associated with a nondipping pattern (3 %). Left ventricular hypertrophy was present in 100 % of patients, heart failure in 60 % nondippers and 56 % dippers, potential renal insufficiency in 34 % nondippers and 22 % dippers, retinopathy in 31 % non dippers and 11 % dippers, aortic aneurysm was only in nondippers. Conclusion: Early morning surge is a predictor of hypertensive target organ damage, being a dipper or nondipper patient with isolated systolic hypertension, might not make a difference depending on one's own degree of target organ damage and diurnal variation (Fig. 2, Ref. 30). Full Text in PDF www.elis.sk.
引用
收藏
页码:150 / 154
页数:5
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