Role of kruppel-like transcription factors in adipogenesis

被引：127
作者：
Wu, Zeni [1 ]
Wang, Suqing [1 ]
机构：
[1] Wuhan Univ, Sch Publ Hlth, Wuhan 430072, Peoples R China
来源：
DEVELOPMENTAL BIOLOGY | 2013年 / 373卷 / 02期
关键词：
Kruppel-like factor; Adipocyte; Adipogenesis; Transcription; ZINC-FINGER PROTEIN; ACTIVATED-RECEPTOR-GAMMA; BROWN ADIPOSE-TISSUE; PPAR-GAMMA; GENE-EXPRESSION; C/EBP-BETA; ADIPOCYTE DIFFERENTIATION; TUMOR-SUPPRESSOR; BINDING PROTEIN; STIMULATES ADIPOGENESIS;
D O I：
10.1016/j.ydbio.2012.10.031
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The zinc-finger transcription factors of the kruppel-like factor family (KLF) are critical in many physiological and pathological processes including cell proliferation, differentiation, inflammation, and apoptosis. Recently, there is increasing evidence that suggests these KLFs have an important role in fat biology. This review summarizes the role of KLFs in lipid metabolism, especially in adipogenesis, and reveals the relationship networks among members of KLF family in differentiation. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码：235 / 243
页数：9
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