Atypical Ductal Hyperplasia of the Breast Diagnosed by Ultrasonographically Guided Core Needle Biopsy

被引:5
作者
Hsu, H. -H. [1 ]
Yu, J. -C. [2 ]
Hsu, G. -C. [1 ]
Yu, C. -P. [3 ]
Chang, W. -C. [1 ]
Tung, H. -J. [4 ]
Lin, W. -C. [1 ]
Tsai, S. -H. [5 ]
Huang, G. -S. [1 ]
机构
[1] Triserv Gen Hosp, Natl Def Med Ctr, Dept Radiol, Taipei 114 5, Taiwan
[2] Triserv Gen Hosp, Natl Def Med Ctr, Div Gen Surg, Dept Surg, Taipei 114 5, Taiwan
[3] Triserv Gen Hosp, Natl Def Med Ctr, Dept Pathol, Taipei 114 5, Taiwan
[4] Asia Univ, Dept Healthcare Adm, Taichung, Taiwan
[5] Triserv Gen Hosp, Natl Def Med Ctr, Dept Emergency Med, Taipei 114 5, Taiwan
来源
ULTRASCHALL IN DER MEDIZIN | 2012年 / 33卷 / 05期
关键词
breast; ultrasound; mammography; VACUUM-ASSISTED BIOPSY; SURGICAL EXCISION; LESIONS; MAMMOGRAPHY; CANCER; UNDERESTIMATION; VARIABILITY; MALIGNANCY; DISEASE; BENIGN;
D O I
10.1055/s-0029-1245877
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Purpose: We analysed the ultrasonographic (US) features of atypical ductal hyperplasia (ADH) of the breast diagnosed by US-guided core needle biopsy (CNB) with the aim of identifying factors that affect the underestimation of ADH. Materials and Methods: A total of 134 ADH lesions sampled by US-guided CNB were reviewed retrospectively. All lesions were evaluated for pattern, size, lesion characteristics and margins, and the corresponding surgical outcome or imaging follow-up was obtained. Each patient's clinical and radiological features were analysed to identify factors involved in ADH underestimation. Results: The prevalence of malignancy in each pattern of lesions following surgical excision was 32/81 (40%) for solid masses, 14/31 (45%) for ductal patterns, 5/17(29%) for complex cystic lesions and 2/5 (40%) for architectural distortions. Based on the results of surgical and US follow-up, none of the category 3 lesions was proven to be a malignancy. Malignancy was found in 17(21%) of the 80 BI-RADS (Breast Imaging Reporting and Data System) category 4a lesions, 20 (74%) of the 27 category 4b lesions, 12 (92%) of the 13 category 4c lesions, and four (100%) of the four category 5 lesions. Lesions with a higher US assessment category, lacking circumscribed margins, or a mammographic finding of suspected malignancy were all significantly associated with underestimation (p < 0.05 for each). Conclusion: US is useful in evaluating ADH lesions and in clarifying the indication for biopsy of these lesions. Familiarity with the frequency associated with malignancy for each feature will improve the utility of US in the work-up of these breast abnormalities.
引用
收藏
页码:447 / 454
页数:8
相关论文
共 29 条
  • [1] Sonography of solid breast lesions: Observer variability of lesion description and assessment
    Baker, JA
    Kornguth, PJ
    Soo, MS
    Walsh, R
    Mengoni, P
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 1999, 172 (06) : 1621 - 1625
  • [2] Cystic lesions of the breast: Sonographic-pathologic correlation
    Berg, WA
    Campassi, CI
    Ioffe, OB
    [J]. RADIOLOGY, 2003, 227 (01) : 183 - 191
  • [3] Predictive factors for breast cancer in patients diagnosed atypical ductal hyperplasia at core needle biopsy
    Chae, Byung Joo
    Lee, Ahwon
    Song, Byung Joo
    Jung, Sang Seol
    [J]. WORLD JOURNAL OF SURGICAL ONCOLOGY, 2009, 7
  • [4] D'Orsi C.J., 2003, Breast imaging reporting and data system (BI-RADS) breast imaging atlas
  • [5] Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: Results of surgical excision
    Darling, MLR
    Smith, DN
    Lester, SC
    Kaelin, C
    Selland, DLG
    Denison, CM
    DiPiro, PJ
    Rose, DI
    Rhei, E
    Meyer, JE
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 2000, 175 (05) : 1341 - 1346
  • [6] RISK-FACTORS FOR BREAST-CANCER IN WOMEN WITH PROLIFERATIVE BREAST DISEASE
    DUPONT, WD
    PAGE, DL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1985, 312 (03) : 146 - 151
  • [7] Is surgical biopsy mandatory in case of atypical ductal hyperplasia on 11-gauge core needle biopsy? a retrospective study of 300 patients
    Forgeard, Caroline
    Benchaib, Medhi
    Guerin, Nicole
    Thiesse, Philippe
    Mignotte, Herve
    Faure, Christelle
    Clement-Chassagne, Catherine
    Treilleux, Isabelle
    [J]. AMERICAN JOURNAL OF SURGERY, 2008, 196 (03) : 339 - 345
  • [8] Fu CY, 2010, ULTRASCHALL MED
  • [9] Ultrasound-guided, vacuum-assisted, percutaneous excision of breast lesions: An accurate technique in the diagnosis of atypical ductal hyperplasia
    Grady, I
    Gorsuch, H
    Wilburn-Bailey, S
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2005, 201 (01) : 14 - 17
  • [10] Underestimation of malignancy of breast core-needle biopsy - Concepts and precise overall and category-specific estimates
    Houssami, Nehmat
    Ciatto, Stefano
    Ellis, Ian
    Ambrogetti, Daniela
    [J]. CANCER, 2007, 109 (03) : 487 - 495