Association between gefitinib and hemorrhagic cystitis and severely contracted bladder: a case report

被引：5

作者：

Arakawa, Maki ^{[1
]}

Nakamura, Kogenta ^{[2
]}

Yamada, Yoshiaki ^{[2
]}

Rosser, Charles J. ^{[3
]}

Tobiume, Motoi ^{[2
]}

Saito, Hiroko ^{[1
]}

Hasegawa, Takaaki ^{[1
]}

Honda, Nobuaki ^{[2
]}

机构：

[1] Aichi Med Univ Hosp, Dept Hosp Pharm, Nagakute, Aichi 4801195, Japan

[2] Aichi Med Univ, Dept Urol, Sch Med, Nagakute, Aichi 4801195, Japan

[3] Univ Florida, Dept Urol, Gainesville, FL USA

来源：

BMC UROLOGY | 2010年 / 10卷

关键词：

Epidermal Growth Factor Receptor; Gefitinib; Lower Urinary Tract Symptom; Moxifloxacin; Hemorrhagic Cystitis;

D O I：

10.1186/1471-2490-10-6

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Gefitinib remains an excellent treatment option for patients with a variety of cancers, including non small cell lung cancer (NSCLC). However, clinicians must be aware of the potential of gefitinib to cause an inflammatory reaction in the skin, lungs and bladder. Case Presentation: We present a case on hemorrhagic cystitis and severaly contracted bladder in a patient with NSCLC on gefitinib. Conclusions: Further studies are needed to substantiate the association of gefitinib therapy with hemorrhagic cystitis and contracted bladder.

引用

页数：3

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