Dihydrophencomycin methyl ester, a new phenazine derivative from a marine Streptomycete

被引:43
作者
Pusecker, K
Laatsch, H
Helmke, E
Weyland, H
机构
[1] UNIV GOTTINGEN,DEPT ORGAN CHEM,D-37077 GOTTINGEN,GERMANY
[2] ALFRED WEGENER INST POLAR & MARINE RES,D-27570 BREMERHAVEN,GERMANY
关键词
D O I
10.7164/antibiotics.50.479
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The novel 5,10-dihydrophencomycin methyl ester (4) and the known microbial metabolites (2-hydroxyphenyl)-acetamide (1), menaquinone MK9 (II, III, VIII, IX-H8) (2), and phencomycin (3a) were isolated from an unidentified marine Streptomyces sp. and the structures were elucidated by NMR methods. Compound 4 shows weak antibiotic activity against Escherichia coli and Bacillus subtilis.
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页码:479 / 483
页数:5
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