Oxidative trimerization of indoles via water-assisted visible-light photoredox catalysis and the study of their anti-cancer activities

被引：14

作者：

Cheng, Li-Ting ^{[1
]}

Luo, Sheng-Qi ^{[1
]}

Hong, Bor-Cherng ^{[1
]}

Chen, Chia-Ling ^{[2
]}

Li, Wen-Shan ^{[2
]}

Lee, Gene-Hsiang ^{[3
]}

机构：

[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Chiayi 621, Taiwan

[2] Acad Sinica, Inst Chem, Taipei 115, Taiwan

[3] Natl Taiwan Univ, Instrumentat Ctr, Taipei 106, Taiwan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2020年 / 18卷 / 32期

关键词：

QUATERNARY CARBON CENTERS; VIBRIO-PARAHAEMOLYTICUS; DEAROMATIZATION; BACTERIUM; FUNCTIONALIZATION; TEMPO; PHOTOCATALYSIS; OXYGENATION; ALKALOIDS; COMPLEX;

D O I：

10.1039/d0ob01298j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Incorporation of water has been revealed to successfully facilitate visible-light photoredox catalysis of indole leading to increased production of C2-quaternary indolinone. The water-promoted photoreaction of indole under catalyst-free conditions by a household compact fluorescence light was also demonstrated. The antiproliferative activity of the synthesized indolinones was evaluated against three human cancer cell lines.

引用

页码：6247 / 6252

页数：6

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